KARS1
KARS1,全稱為賴氨酰-tRNA合成酶1,也被稱為賴氨酸氨酰-tRNA合成酶。該蛋白質在細胞內負責將賴氨酸這種氨基酸連接到對應的tRNA分子上,是蛋白質合成過程中的關鍵步驟。KARS1蛋白的異常變異會導致一系列罕見的綜合征,包括神經系統損傷、心臟和肝臟疾病以及聽力損失。研究表明,這些變異會影響KARS1蛋白的正常功能,進而干擾蛋白質的合成,導致細胞和組織的損傷。目前,針對KARS1相關疾病的治療方法有限,主要集中在支持性治療上。然而,隨著對KARS1蛋白功能和變異的深入研究,科學家們正在探索新的治療策略,例如通過藥物調節KARS1蛋白的表達或活性,以期改善患者的癥狀和預后。
熱銷產品
KARS Antibody (CSB-PA04689A0Rb)
驗證數據

Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: KARS antibody at 2.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 69, 72 kDa
Observed band size: 69 kDa

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA04689A0Rb at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA04689A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
KARS1 Antibodies
KARS1 for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA011986GA01HU | KARS Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA163096 | KARS Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA056745 | KARS Antibody | Human,Mouse | ELISA,IHC |
CSB-PA04689A0Rb | KARS Antibody | Human | ELISA, WB, IHC, IF |
CSB-PA04689B0Rb | KARS Antibody, HRP conjugated | Human | ELISA |
CSB-PA04689D0Rb | KARS Antibody, Biotin conjugated | Human | ELISA |
KARS1 Proteins
KARS1 Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP618973HU CSB-EP618973HU CSB-BP618973HU CSB-MP618973HU CSB-EP618973HU-B |
Recombinant Human Lysine--tRNA ligase (KARS) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |