IL1RAP
IL1RAP，即白細(xì)胞介素1受體輔助蛋白，別名IL-1RAcP、C3orf13等，是IL-1信號(hào)通路的關(guān)鍵分子。它源自基因表達(dá)，通過與IL-1受體結(jié)合，增強(qiáng)IL-1信號(hào)傳導(dǎo)，激活下游炎癥通路，調(diào)節(jié)免疫細(xì)胞活性與炎癥反應(yīng)。IL1RAP在免疫調(diào)節(jié)、細(xì)胞增殖分化中扮演重要角色，其異常表達(dá)關(guān)聯(lián)多種疾病，如癌癥與自身免疫病。因此，IL1RAP成為疾病治療的新靶點(diǎn)，針對(duì)其的療法正逐步進(jìn)入臨床試驗(yàn)。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL1RAP at 2 μg/ml can bind Anti-IL1RAP recombinant antibody (CSB-RA878844MA1HU). The EC50 is 0.9667-1.477 ng/mL.
The purity of IL1RAP was greater than 95% as determined by SEC-HPLC
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL1RAP at 2 μg/ml can bind Anti-IL1RAP recombinant antibody (CSB-RA878844MA1HU). The EC50 is 0.9099-1.181 ng/mL.
The purity of IL1RAP was greater than 95% as determined by SEC-HPLC
IL1RAP Antibodies
IL1RAP for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA878844ESR1HU | IL1RAP Antibody | Human | ELISA, IHC |
| CSB-PA238165 | IL1RAP Antibody | Human,Mouse,Rat | ELISA,IHC |
IL1RAP Proteins
IL1RAP Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011623MOW1 CSB-EP011623MOW1 CSB-BP011623MOW1 CSB-MP011623MOW1 CSB-EP011623MOW1-B |
Recombinant Macaca mulatta (Rhesus macaque) Interleukin-1 receptor accessory protein (IL1RAP), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011623MOW | Recombinant Macaca mulatta (Rhesus macaque) Interleukin-1 receptor accessory protein (IL1RAP) | in vitro E.coli expression system |
IL1RAP Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP730751MO CSB-EP730751MO CSB-BP730751MO CSB-EP730751MO-B |
Recombinant Mouse Interleukin-1 receptor accessory protein (Il1rap), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
IL1RAP Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP733954RA CSB-BP733954RA CSB-EP733954RA-B |
Recombinant Rat Interleukin-1 receptor accessory protein (Il1rap), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
IL1RAP Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP878844HU CSB-EP878844HU CSB-BP878844HU CSB-EP878844HU-B |
Recombinant Human Interleukin-1 receptor accessory protein (IL1RAP), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP878844HU | Recombinant Human Interleukin-1 receptor accessory protein (IL1RAP), partial (Active) | Mammalian cell |
