IL17C
Interleukin-17C is a protein in humans that is encoded by IL17C gene. Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
IL17C Antibodies
IL17C for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA809269 | IL17C Antibody | Human | ELISA,WB,IHC |
| CSB-PA959846 | IL17C Antibody | Human | ELISA,WB,IHC |
| CSB-PA301181 | IL17C Antibody | Human | IHC,ELISA |
IL17C Proteins
IL17C Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP889169HU CSB-EP889169HU CSB-BP889169HU CSB-MP889169HU CSB-EP889169HU-B |
Recombinant Human Interleukin-17C (IL17C) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17C ELISA Kit
IL17C ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
|---|---|---|---|
| CSB-E15917h | Human Interleukin17C (IL17C) ELISA Kit | serum, plasma, tissue homogenates | 0.039 ng/ml |
