HIPK2
HIPK2，即同源結構域相互作用蛋白激酶2，別名PRO0593、hHIPk2。HIPK2是一種絲氨酸/蘇氨酸激酶，屬于同源結構域相互作用蛋白激酶家族。HIPK2與同源結構域轉錄因子和許多其他轉錄因子（如p53）相互作用，可以根據轉錄因子及其亞細胞定位同時充當共抑制因子和共激活因子。HIPK2可以誘導或抑制轉錄，調節細胞分化、增殖及凋亡。HIPK2經過泛素化、小泛素樣修飾（SUMO）化、乙酰化、磷酸化等翻譯后修飾來發揮其生物功能。HIPK2能促進細胞凋亡，是潛在的腫瘤抑制因子和DNA損傷相關激酶，通過磷酸化反應作用于不同的下游靶點來激活凋亡進程。HIPK2還參與組織器官的形成、腫瘤的發生和發展。
熱銷產品
HIPK2 Antibody (CSB-PA867138LA01HU)
驗證數據
IHC image of CSB-PA867138LA01HU diluted at 1:500 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA867138LA01HU diluted at 1:500 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
HIPK2 Antibodies
HIPK2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA867138LA01HU | HIPK2 Antibody | Human | ELISA, IHC |
| CSB-PA867138LB01HU | HIPK2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA867138LC01HU | HIPK2 Antibody, FITC conjugated | Human | |
| CSB-PA867138LD01HU | HIPK2 Antibody, Biotin conjugated | Human | ELISA |
HIPK2 Proteins
HIPK2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP867138HU CSB-EP867138HU CSB-BP867138HU CSB-MP867138HU CSB-EP867138HU-B |
Recombinant Human Homeodomain-interacting protein kinase 2 (HIPK2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HIPK2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP882585MO CSB-EP882585MO CSB-BP882585MO CSB-MP882585MO CSB-EP882585MO-B |
Recombinant Mouse Homeodomain-interacting protein kinase 2 (Hipk2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HIPK2 Proteins for Mesocricetus auratus (Golden hamster)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP895752MRG CSB-EP895752MRG CSB-BP895752MRG CSB-MP895752MRG CSB-EP895752MRG-B |
Recombinant Mesocricetus auratus Homeodomain-interacting protein kinase 2 (Hipk2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
