GTF2H1
General transcription factor IIH subunit 1 is a protein in humans that is encoded by GTF2H1 gene. Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
GTF2H1 Antibodies
GTF2H1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA010007GA01HU | GTF2H1 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA934028 | GTF2H1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA009042 | GTF2H1 Antibody | Human,Mouse | WB, IHC, ELISA |
GTF2H1 Proteins
GTF2H1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP010007HU CSB-EP010007HU CSB-BP010007HU CSB-MP010007HU CSB-EP010007HU-B |
Recombinant Human General transcription factor IIH subunit 1 (GTF2H1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GTF2H1 Proteins for Dictyostelium discoideum (Slime mold)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP681895DKK CSB-EP681895DKK CSB-BP681895DKK CSB-MP681895DKK CSB-EP681895DKK-B |
Recombinant Dictyostelium discoideum General transcription factor IIH subunit 1 (gtf2h1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GTF2H1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP861603MO CSB-EP861603MO CSB-BP861603MO CSB-MP861603MO CSB-EP861603MO-B |
Recombinant Mouse General transcription factor IIH subunit 1 (Gtf2h1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
