GPR84
GPR84是一種G蛋白偶聯受體，即中鏈脂肪酸受體。它在多種細胞類型中表達，包括中性粒細胞等免疫細胞。GPR84的作用機制涉及通過與脂肪酸等配體結合，激活下游信號通路，影響細胞的遷移、脫顆粒和氧化應激反應。在信號傳導方面，GPR84能夠通過Lyn-AKT/ERK通路進行信號轉導，進而調控氧化應激關鍵蛋白p47PHOX的活性，參與活性氧簇（ROS）的產生。在生物學意義上，GPR84參與調控炎癥反應和免疫應答，尤其在急性肺損傷（ALI）等疾病中發揮重要作用，其表達的變化與肺部炎癥因子水平、肺組織損傷程度密切相關。因此，GPR84被認為是治療急性肺損傷等炎癥性疾病的潛在藥物靶點。
熱銷產品
Recombinant Human G-protein coupled receptor 84 (GPR84), partial (CSB-YP865107HU2)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
The purity of GPR84 was greater than 90% as determined by SEC-HPLC
GPR84 Antibody (CSB-PA865107LA01HU)
驗證數據
Immunofluorescent analysis of Hela cells using CSB-PA865107LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
GPR84 Antibodies
GPR84 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA865107LA01HU | GPR84 Antibody | Human | ELISA, IF |
| CSB-PA865107LB01HU | GPR84 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA865107LC01HU | GPR84 Antibody, FITC conjugated | Human | |
| CSB-PA865107LD01HU | GPR84 Antibody, Biotin conjugated | Human | ELISA |
GPR84 Proteins
GPR84 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP644417BO1 CSB-EP644417BO1 CSB-BP644417BO1 CSB-MP644417BO1 CSB-EP644417BO1-B |
Recombinant Bovine G-protein coupled receptor 84 (GPR84), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF644417BO | Recombinant Bovine G-protein coupled receptor 84 (GPR84) | in vitro E.coli expression system |
GPR84 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP807541MO1 CSB-EP807541MO1 CSB-BP807541MO1 CSB-MP807541MO1 CSB-EP807541MO1-B |
Recombinant Mouse G-protein coupled receptor 84 (Gpr84), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF807541MO | Recombinant Mouse G-protein coupled receptor 84 (Gpr84) | in vitro E.coli expression system |
GPR84 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP865107HU1 CSB-EP865107HU1 CSB-BP865107HU1 CSB-MP865107HU1 CSB-EP865107HU1-B |
Recombinant Human G-protein coupled receptor 84 (GPR84), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF865107HU | Recombinant Human G-protein coupled receptor 84 (GPR84) | in vitro E.coli expression system |
| CSB-YP865107HU2 | Recombinant Human G-protein coupled receptor 84 (GPR84), partial | Yeast |
