GFRA4
GFRA4，全稱(chēng)為GDNF家族受體α-4，也被稱(chēng)為 persephin 受體。它是一種細(xì)胞表面受體，與persephin結(jié)合，并介導(dǎo)RET酪氨酸激酶受體的激活。GFRA4在成人甲狀腺中表達(dá)量較高，同時(shí)在胎兒腎上腺和甲狀腺中也有低水平表達(dá)。該蛋白與多種疾病相關(guān)，如Hirschsprung病，可能與神經(jīng)系統(tǒng)的發(fā)育和功能有關(guān)。目前，針對(duì)GFRA4的抗體產(chǎn)品已研發(fā)出來(lái)，用于研究和治療相關(guān)疾病。此外，GFRA4也是藥物研發(fā)的熱點(diǎn)靶點(diǎn)之一，未來(lái)可能會(huì)有更多針對(duì)該蛋白的藥物問(wèn)世。
熱銷(xiāo)產(chǎn)品
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA271998(GFRA4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA271998(GFRA4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
GFRA4 Antibodies
GFRA4 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA050010 | GFRA4 Antibody | Human | WB, ELISA |
| CSB-PA271998 | GFRA4 Antibody | Human | ELISA,IHC |
| CSB-PA693066 | GFRA4 Antibody | Human | ELISA,WB,IHC |
GFRA4 Proteins
GFRA4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP863936HU CSB-EP863936HU CSB-BP863936HU CSB-MP863936HU CSB-EP863936HU-B |
Recombinant Human GDNF family receptor alpha-4 (GFRA4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
