ERCC8
DNA excision repair protein ERCC-8 is a protein in humans that is encoded by ERCC8 gene. Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitment of XAB2, HMGN1 and TCEA1/TFIIS to a transcription-coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes.
ERCC8 Proteins
ERCC8 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP621655HU CSB-EP621655HU CSB-BP621655HU CSB-MP621655HU CSB-EP621655HU-B |
Recombinant Human DNA excision repair protein ERCC-8 (ERCC8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ERCC8 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP701699BO CSB-EP701699BO CSB-BP701699BO CSB-MP701699BO CSB-EP701699BO-B |
Recombinant Bovine DNA excision repair protein ERCC-8 (ERCC8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ERCC8 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP804034MO CSB-EP804034MO CSB-BP804034MO CSB-MP804034MO CSB-EP804034MO-B |
Recombinant Mouse DNA excision repair protein ERCC-8 (Ercc8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
