CD80

CD80，全稱為Cluster of Differentiation 80，也被稱為B7-1，是一種位于3號染色體的人類基因，屬于免疫球蛋白超家族中的B7蛋白質(zhì)家族。CD80在樹突狀細(xì)胞、活化的B細(xì)胞、巨噬細(xì)胞以及T細(xì)胞上表達(dá)，與CD86（B7-2）形成共刺激信號，對T細(xì)胞活化起到重要作用。CD80在免疫反應(yīng)中扮演著關(guān)鍵角色，與多種疾病如紅斑性狼瘡有關(guān)。近年來，針對CD80的藥物研發(fā)取得了顯著進(jìn)展，如軒竹生物的KM602，作為一種CD80融合蛋白，有望成為治療晚期實體瘤的新選擇。

熱銷產(chǎn)品

Recombinant Human T-lymphocyte activation antigen CD80 (CD80), partial (CSB-MP004959HU1)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CD80 Recombinant Monoclonal Antibody (CSB-RA246383A0HU)

驗證數(shù)據(jù)

Western Blot
Positive WB detected in: Raji whole cell lysate
All lanes: CD80 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 34, 30, 19 kDa
Observed band size: 60 kDa

IHC image of CSB-RA246383A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Immunoprecipitating CD80 in Raji whole cell lysate
Lane 1: Rabbit control IgG instead of CSB-RA246383A0HU in Raji whole cell lysate. For western blotting,a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: CSB-RA246383A0HU(2μg)+ Raji whole cell lysate(500μg)
Lane 3: Raji whole cell lysate (10μg)

CD80 Antibody

CD80 Protein

CD80 ELISA Kit

CD80 Antibodies

CD80 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA004959GA01HU	CD80 Antibody	Human	ELISA,WB
CSB-PA277650	CD80 Antibody	Human	ELISA,IHC
CSB-PA130815	CD80 Antibody	Human	ELISA,IHC
CSB-PA129040	CD80 Antibody	Human	IHC,ELISA
CSB-RA246383A0HU	CD80 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IP

CD80 Proteins

CD80 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP004959MO1 CSB-EP004959MO1 CSB-BP004959MO1 CSB-MP004959MO1 CSB-EP004959MO1-B	Recombinant Mouse T-lymphocyte activation antigen CD80 (Cd80), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF004959MO	Recombinant Mouse T-lymphocyte activation antigen CD80 (Cd80)	in vitro E.coli expression system

CD80 Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP004959RB1 CSB-EP004959RB1 CSB-BP004959RB1 CSB-MP004959RB1 CSB-EP004959RB1-B	Recombinant Rabbit T-lymphocyte activation antigen CD80 (CD80), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF004959RB	Recombinant Rabbit T-lymphocyte activation antigen CD80 (CD80)	in vitro E.coli expression system

CD80 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP004959HU1 CSB-EP004959HU1 CSB-BP004959HU1 CSB-EP004959HU1-B	Recombinant Human T-lymphocyte activation antigen CD80 (CD80), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-CF004959HU	Recombinant Human T-lymphocyte activation antigen CD80 (CD80)	in vitro E.coli expression system
CSB-MP004959HU1	Recombinant Human T-lymphocyte activation antigen CD80 (CD80), partial	Mammalian cell
CSB-CF1054HU	Recombinant Human T-lymphocyte activation antigen CD80 (CD80)	in vitro E.coli expression system
CSB-MP1054HU	Recombinant Human T-lymphocyte activation antigen CD80 (CD80)-VLPs	Mammalian cell