CD147
CD147，（也稱為Basigin或EMMPRIN），是一種跨膜蛋白，屬于免疫球蛋白超家族，其結構含有一個細胞外N端和一個胞內C端。它有一個Ig-like（免疫球蛋白樣）細胞外結構域，可與其他蛋白質發生相互作用。CD147廣泛表達在許多細胞類型中，包括免疫細胞、白血球、紅血球、神經細胞、膠質細胞、腫瘤細胞等。它在細胞間黏附和遷移過程中發揮重要作用，并參與多種生物學過程，如細胞的增殖、侵襲、轉移以及免疫細胞的活化和炎癥反應等。 在腫瘤學中，CD147被認為是一種腫瘤相關標志物，因為它在多種腫瘤細胞表面的表達水平明顯升高，與腫瘤細胞的侵襲和轉移有關。CD147還參與調節腫瘤微環境中的細胞間相互作用，對腫瘤的生長和進展具有一定的影響。此外，CD147在免疫調節和感染過程中也發揮著重要作用。它與病原體感染、炎癥反應和免疫細胞的活化和遷移等過程密切相關。是疾病治療和新藥開發的潛在靶點。
熱銷產品
● Recombinant Human Basigin(BSG),partial (Active)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized CD147 at 2 μg/ml can bind Anti-CD147 recombinant Antibody, the EC50 is 21.95-33.12 ng/ml.
● CD147 Recombinant Monoclonal Antibody CSB-RA002831A0HU
驗證數據
Positive WB detected in: HepG2 whole cell lysate, ntera2 whole cell lysate, A549 whole cell lysate, U251 whole cell lysate
All lanes: CD147 antibody at 1:1000
Secondary
Goat polyclonal to mouse IgG at 1/50000 dilution
Predicted band size: 42, 29, 23, 19 KDa
Observed band size: 35, 50-60 KDa
CD147 Antibodies
CD147 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA11759A0Rb | BSG Antibody | Human | ELISA, WB, IHC |
| CSB-PA11759C0Rb | BSG Antibody, FITC conjugated | Human | |
| CSB-PA002831GA01HU | BSG Antibody | Human | ELISA,WB,IHC |
| CSB-PA11759B0Rb | BSG Antibody, HRP conjugated | Human | ELISA |
| CSB-PA11759D0Rb | BSG Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA002331 | BSG Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA005853 | BSG Antibody | Human | WB, ELISA |
| CSB-PA993569 | BSG Antibody | Human | ELISA,IHC |
| CSB-PA570608 | BSG Antibody | Human | ELISA,WB,IHC |
| CSB-RA002831A0HU | CD147 Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IF, FC |
CD147 Proteins
CD147 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002831MO1 CSB-EP002831MO1 CSB-BP002831MO1 CSB-MP002831MO1 CSB-EP002831MO1-B |
Recombinant Mouse Basigin (Bsg), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF002831MO | Recombinant Mouse Basigin (Bsg) | in vitro E.coli expression system |
CD147 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002831HU CSB-EP002831HU CSB-BP002831HU CSB-EP002831HU-B |
Recombinant Human Basigin (BSG), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-RP117574h | Recombinant Human Basigin (BSG), partial | E.coli |
| CSB-CF002831HU | Recombinant Human Basigin (BSG) | in vitro E.coli expression system |
| CSB-MP002831HU | Recombinant Human Basigin (BSG), partial | Mammalian cell |
| CSB-MP002831HUf3 | Recombinant Human Basigin (BSG), partial | Mammalian cell |
| CSB-MP002831HU1 | Recombinant Human Basigin (BSG), partial (Active) | Mammalian cell |
CD147 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002831RA1 CSB-EP002831RA1 CSB-BP002831RA1 CSB-MP002831RA1 CSB-EP002831RA1-B |
Recombinant Rat Basigin (Bsg), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF002831RA | Recombinant Rat Basigin (Bsg) | in vitro E.coli expression system |
CD147 Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP631727RB CSB-EP631727RB CSB-BP631727RB CSB-MP631727RB CSB-EP631727RB-B |
Recombinant Rabbit Basigin (BSG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD147 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP857519DXU CSB-EP857519DXU CSB-BP857519DXU CSB-MP857519DXU CSB-EP857519DXU-B |
Recombinant Cricetulus griseus Basigin (BSG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD147 ELISA Kit
CD147 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E12994h | Human Cluster of differentiation 147,CD147 Elisa Kit | serum, plasma | 3.12 pg/mL |
