CCR6
CCR6在細胞的信號傳導中扮演重要角色，作為G蛋白偶聯受體的成員。它包含了七個跨膜區域，兩個胞漿區域和一個胞外區域。這種結構使得CCR6能夠與其配體結合并傳遞信號其配體包括CCL20（也稱為MIP-3α），它能夠引導特定類型的免疫細胞向特定組織或器官遷移。除了免疫細胞的遷移外，CCR6也在其他生理和病理過程中發揮作用，例如炎癥、腫瘤轉移和神經發育。CCR6通過激活多種信號通路來介導其生物學效應。主要的信號通路包括G蛋白偶聯受體信號通路（通過激活G蛋白）和非G蛋白偶聯受體信號通路（通過激活絲裂原激活蛋白激酶（MAPK）信號通路等）。這些信號通路的激活可以導致細胞遷移、增殖、分化和其他生物學響應。
熱銷產品
Recombinant Human C-C chemokine receptor type 6(CCR6)-VLPs (Active)
驗證數據
CSB-MP004845HU is detected by Mouse anti-6*His monoclonal antibody. The two bands respectively correspond to monomer, Homodimer.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CCR6 at 10μg/mL can bind Anti-CCR6 recombinant antibody (CSB-RA004845MA1HU)， the EC50 is 44.79-56.10 ng/mL.VLPs (CSB-MP3838) is negative control.
CCR6 Antibodies
CCR6 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA004845EA01HU | CCR6 Antibody | Human | ELISA, WB |
| CSB-PA004845EC01HU | CCR6 Antibody, FITC conjugated | Human | |
| CSB-PA943255 | CCR6 Antibody | Human | ELISA,WB,IHC |
| CSB-PA244343 | CCR6 Antibody | Human | ELISA,IHC |
| CSB-RA004845MA1HU | CCR6 Recombinant Monoclonal Antibody | Human | ELISA |
| CSB-RA004845MA2HU | CCR6 Recombinant Monoclonal Antibody | Human | Non-conjugated |
CCR6 Proteins
CCR6 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004845HU1 CSB-BP004845HU1 CSB-MP004845HU1 CSB-EP004845HU1-B |
Recombinant Human C-C chemokine receptor type 6 (CCR6), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004845HU | Recombinant Human C-C chemokine receptor type 6 (CCR6) | in vitro E.coli expression system |
| CSB-CF004845HUa2 | Recombinant Human C-C chemokine receptor type 6 (CCR6) | in vitro E.coli expression system |
| CSB-EP004845HU1 | Recombinant Human C-C chemokine receptor type 6 (CCR6), partial | E.coli |
| CSB-MP004845HU | Recombinant Human C-C chemokine receptor type 6(CCR6)-VLPs (Active) | Mammalian cell |
CCR6 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004845MO1 CSB-EP004845MO1 CSB-BP004845MO1 CSB-MP004845MO1 CSB-EP004845MO1-B |
Recombinant Mouse C-C chemokine receptor type 6 (Ccr6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004845MO | Recombinant Mouse C-C chemokine receptor type 6 (Ccr6) | in vitro E.coli expression system |
