BRD8
May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair.
BRD8 Antibodies
BRD8 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA002805GA01HU | BRD8 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA880933LA01HU | BRD8 Antibody | Human | ELISA, IHC |
BRD8 Proteins
BRD8 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP837137MO CSB-EP837137MO CSB-BP837137MO CSB-MP837137MO CSB-EP837137MO-B |
Recombinant Mouse Bromodomain-containing protein 8 (Brd8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRD8 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP880933HU CSB-EP880933HU CSB-BP880933HU CSB-MP880933HU CSB-EP880933HU-B |
Recombinant Human Bromodomain-containing protein 8 (BRD8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
