ATF6
Cyclic AMP-dependent transcription factor ATF-6 alpha is a protein in humans that is encoded by ATF6 gene. Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.
ATF6 Antibodies
ATF6 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA002277LA01HU | ATF6 Antibody | Human | ELISA, IHC, IF |
| CSB-PA002277LB01HU | ATF6 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA002277LC01HU | ATF6 Antibody, FITC conjugated | Human | |
| CSB-PA002277LD01HU | ATF6 Antibody, Biotin conjugated | Human | ELISA |
ATF6 Proteins
ATF6 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002277HU CSB-EP002277HU CSB-BP002277HU CSB-MP002277HU CSB-EP002277HU-B |
Recombinant Human Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF002277HU(A4) | Recombinant Human Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6) | in vitro E.coli expression system |
