Recombinant Xenopus laevis E3 ubiquitin-protein ligase synoviolin A (syvn1-a)

in vitro E.coli expression system

中文名稱：

有爪蟾蜍syvn1-a重組蛋白
貨號：

CSB-CF743976XBE
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

syvn1-a
Uniprot No.：

Q6NRL6
別名：

syvn1-a; hrd1-a; E3 ubiquitin-protein ligase synoviolin A; RING-type E3 ubiquitin transferase synoviolin A; Synovial apoptosis inhibitor-1-A
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

Full Length of Mature Protein
表達區域：

17-605
氨基酸序列

YYLKNQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKFMGKVFFGQLRAAEMEHLLERSW YAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMERSPNISWLFHFRIL ALMLLLGVLDAFFVSHAYHSLVIRGASVQLVFGFEYAILMTVILTVFIKYILHSVDLQSE NPWDNKAVYMLYTELFTGFIKVLLYVAFMTIMVKVHTFPLFAIRPMYLAMRQFKKAVTDA IMSRRAIRNMNTLYPDATAEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQR QQTCPTCRMDVLRASLPTQPQTPTEQQNQHQNQAQQQPTPVIPPQPNFPPGILPPFPPGM FPLWPPMGPFPPVPGAPGGNPPDEANPGSSSGSSPRPGETSNVGSESQPGAALPGFPFPP PFLGMPILPPFGLPPMPMPPAGFTGLTDEELRAMEGHERQNLEARLQCLQNIHTLLDAAM LQINQYLTVLASIGPPQPPISSTSTSTSSAASASTAPTTSNISEPVIPVDTTSTVTNTES SQQSAPPAPVSVETLSGAEGGETTTEEPDNVELRRRRLQKLETGTTDSQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins. Protects cells from ER stress-induced apoptosis. Sequesters p53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis.
亞細胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

HRD1 family
數據庫鏈接：

KEGG: xla:431869

UniGene: Xl.18945