Recombinant Tetraodon fluviatilis 5-hydroxytryptamine receptor 2B (htr2b)

in vitro E.coli expression system

中文名稱：

Recombinant Tetraodon fluviatilis 5-hydroxytryptamine receptor 2B(htr2b)
貨號：

CSB-CF848645TLV
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

htr2b
Uniprot No.：

Q8UUG8
別名：

htr2b; 5-hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT2B; Serotonin receptor 2B
種屬：

Tetraodon fluviatilis (Green pufferfish) (Chelonodon fluviatilis)
蛋白長度：

full length protein
表達區域：

1-471
氨基酸序列

MFQAAVGPLQTNISLPEETPGLELNWAALLIVMVIIPTIGGNILVILAVWLEKKLQNATN FFLMSLAVADLLVGLLVMPIALITILYDSDWPLPEPLCPIWLFLDVLFSTASIMHLCAIS LDRYIAIKKPIQHSQYKSRAKVMLKIALVWLISICIAIPIPIKGLRNYPHPNNITFTSNH TCVLKTDTFQEFIIFGSLVAFFIPLTIMMIIYFLTVRVLRKKVYLLRSKVTQRFSYPIIS TVFQREQAANPPQPEQPDSTGNSLARIQEKTDTDGMSSPTGDEKSFRRLSTMGKKSMQTL TNEQRASKVLGIVFLLFVVMWCPFFITNITSALCGPCDANIIGRLMEIFSWVGYVSSGIN PLVYTLFNKTFRQAFTRYITCNYRNFASKEQGRSFRASTVDRMLTHISPRSSVAENAKLF TKQEIKNETTDYRSPLGCLQPSAQTSTGVVLDKILLTHTENCKQEERVSCV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity.
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.
蛋白家族：

G-protein coupled receptor 1 family
組織特異性：

Detected in brain, heart and gut.