Recombinant Saccharomyces cerevisiae Mitochondrial chaperone BCS1 (BCS1)

in vitro E.coli expression system

中文名稱：

Recombinant Saccharomyces cerevisiae Mitochondrial chaperone BCS1(BCS1)
貨號：

CSB-CF002644SVG
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

BCS1
Uniprot No.：

P32839
別名：

BCS1; YDR375C; D9481.17; Mitochondrial chaperone BCS1
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區域：

1-456
氨基酸序列

MSDKPIDIQYDKQATPNLSGVITPPTNETGNDSVREKLSKLVGDAMSNNPYFAAGGGLMI LGTGLAVARSGIIKASRVLYRQMIVDLEIQSKDKSYAWFLTWMAKHPQRVSRHLSVRTNY IQHDNGSVSTKFSLVPGPGNHWIRYKGAFILIKRERSAKMIDIANGSPFETVTLTTLYRD KHLFDDILNEAKDIALKTTEGKTVIYTSFGPEWRKFGQPKAKRMLPSVILDSGIKEGILD DVYDFMKNGKWYSDRGIPYRRGYLLYGPPGSGKTSFIQALAGELDYNICILNLSENNLTD DRLNHLMNNMPERSILLLEDIDAAFNKRSQTGEQGFHSSVTFSGLLNALDGVTSSEETIT FMTTNHPEKLDAAIMRPGRIDYKVFVGNATPYQVEKMFMKFYPGETDICKKFVNSVKELD ITVSTAQLQGLFVMNKDAPHDALKMVSSLRNANHIF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Essential for the expression of the Rieske iron-sulfur protein.
基因功能參考文獻：
1. We found that the absence of non-essential translation factors Rrf1 or Mif3, which act at the recycling/initiation steps, also compensates for the respiratory deficiency of yeast bcs1 mutations PMID: 28888990
2. The ATP dependency of the protein Bcs1 is not just a requirement for its chaperon activity but also a way to couple the rate of complex III biogenesis to the energy-transducing activity of mitochondria. PMID: 24055101
3. The evolutionarily-conserved short alpha helix of Bcs1 in the intermembrane space is an essential element for the chaperone function. PMID: 24361883
4. The oligomeric AAA-ATPase Bcs1 is involved in export of the folded Fe-S domain of Rip1 across the inner membrane and insertion of its transmembrane segment into an assembly intermediate of the cytochrome bc(1) complex. PMID: 22017868
5. residues located at the junction between the Bcs1p-specific and the AAA domains are important for the activity and stability of the protein, and the residue F342 is important for interactions with other partners or substrate proteins. PMID: 19285991
顯示更多

收起更多
亞細胞定位：

Mitochondrion inner membrane; Single-pass membrane protein.
蛋白家族：

AAA ATPase family, BCS1 subfamily
數據庫鏈接：

KEGG: sce:YDR375C

STRING: 4932.YDR375C