Recombinant Mouse Solute carrier family 25 member 46 (Slc25a46)

in vitro E.coli expression system

中文名稱(chēng)：

小鼠Slc25a46重組蛋白
貨號(hào)：

CSB-CF875118MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

基因名：

Slc25a46
Uniprot No.：

Q9CQS4
別名：

Slc25a46; Solute carrier family 25 member 46
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-418
氨基酸序列

MHPRRPEGFDGLGYRGGVRDDPAFGGPFHARSFGSGTELGHWVTTPPDIPGSRNLHWGEK SPSYGVPSAPPTLEGSAEEPFPGGGEGPRPGPSSEQLNRFAGFGIGLASLFTENVLAHPC IVLRRQCQVNYHARHYHLTPFSIINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGII SEFTPLPREVSHKLNPKQIGEHLLLKCLTYMVAMPFYSASLIETVQSEIIRDNTGILECV KEGIGRVIGLGVPHSKRLLPLFSLIFPTVLHGVLHYIISSIIQKIVLLILKRKTYNSHLA ESTSPMQNMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVL PINTQYEGMRDCINTIKQEEGVFGFYKGFGAVIIQYTLHATILQITKMIYSTLLQNSI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.
基因功能參考文獻(xiàn)：
1. we showed that the Slc25a46 disruption caused a fusion/fission imbalance and an abnormal mitochondrial architecture that disturbed mitochondrial metabolism. These data extended the range of phenotypes associated with Slc25a46 dysfunction. Moreover, this Slc25a46 knock-out mouse model should be useful to further elucidate the role of SLC25A46 in mitochondrial dynamics PMID: 28376083
2. Our mutant mice provide a valid model for understanding the mechanistic basis of the complex SLC25A46-mediated pathologies, as well as for screening potential therapeutic interventions. PMID: 28376086
亞細(xì)胞定位：

Mitochondrion outer membrane; Multi-pass membrane protein.
蛋白家族：

Mitochondrial carrier (TC 2.A.29) family
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:67453

STRING: 10090.ENSMUSP00000053325

UniGene: Mm.23896