Recombinant Mouse RING finger protein 186 (Rnf186)

in vitro E.coli expression system

中文名稱：

小鼠Rnf186重組蛋白
貨號：

CSB-CF019864MO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Rnf186
Uniprot No.：

Q9D241
別名：

Rnf186; E3 ubiquitin-protein ligase RNF186; RING finger protein 186
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-226
氨基酸序列

MSCTEAPQPIPAGTTTTSTIIALGPTGRLSISVEGDLECLVCREPYNCARSPKLLSCQHT FCAVCLKLLLYVQEDTWSIPCPLCRKVTAVPGGLICSLRDQEAMVGRLALPCPEVRLCPQ RLVGSAASATRPANWTGEEEQDTVSVNRVAARRLAVHLLLLALVIVLILPFIYPGVIRWV LAFVIALALLMSTLFCCHPQSQNSNWLCPRTLFCREQKQTQITSIA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

E3 ubiquitin protein ligase that is part of an apoptotic signaling pathway activated by endoplasmic reticulum stress. In that process, stimulates the expression of proteins specific of the unfolded protein response (UPR), ubiquitinates BNIP1 and regulates its localization to the mitochondrion and induces calcium release from the endoplasmic reticulum that ultimately leads to cell apoptosis.
基因功能參考文獻：
1. RNF186 maintains gut homeostasis by controlling endoplasmic reticulum stress in colonic epithelia PMID: 27381925
亞細胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein.
數據庫鏈接：

KEGG: mmu:66825

STRING: 10090.ENSMUSP00000111780

UniGene: Mm.252312