Recombinant Mouse Probable low affinity copper uptake protein 2 (Slc31a2)

in vitro E.coli expression system

中文名稱：

小鼠Slc31a2重組蛋白
貨號：

CSB-CF861427MO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Slc31a2
Uniprot No.：

Q9CPU9
別名：

Slc31a2; Probable low affinity copper uptake protein 2; Copper transporter 2; CTR2; Solute carrier family 31 member 2
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-143
氨基酸序列

MPMHFIFSDEAVLLFDFWRVHSPTGMALSVLVVLLLAVLYEGIKVGKAKLLHKTLESLPA TNSQQFILGPDQDSTGSRSTSDNRTRLRWFLCYFGQSLVHVIQVVIGYFVMLAVMSYNTW IFLGVVLGSAVGYYLAYPLLNMT
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in low-affinity copper uptake.
基因功能參考文獻：
1. The increase in granular staining and heparin content is compatible with an impact of Ctr2 on mast cell maturation and, in support of this, the absence of Ctr2 resulted in markedly increased mRNA expression, storage, and enzymatic activity of tryptase. PMID: 26342034
2. In mouse embryo fibroblasts, reduction of CTR1 expression renders cells resistant to cisplatin whereas reduction of CTR2 makes them hypersensitive both in vitro and in vivo. PMID: 24522273
3. Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain. PMID: 24167251
4. Copper transporter 2 regulates the transport of cisplatin through control of the rate of macropinocytosis. PMID: 20930109
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Copper transporter (Ctr) (TC 1.A.56) family, SLC31A subfamily
數據庫鏈接：

KEGG: mmu:20530

STRING: 10090.ENSMUSP00000081578

UniGene: Mm.292539