Recombinant Mouse Probable G-protein coupled receptor 97 (Gpr97)

in vitro E.coli expression system

中文名稱：

Recombinant Mouse Probable G-protein coupled receptor 97(Gpr97)
貨號：

CSB-CF823150MO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Adgrg3
Uniprot No.：

Q8R0T6
別名：

Adgrg3; Gpr97; Adhesion G protein-coupled receptor G3; G-protein coupled receptor 97
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

19-542
氨基酸序列

EETTEEPRNVCRRLQEGHEYDTFDLNDTAQCFTKCGQSEHSPCDVGNLQRYWLNYESYLL ENSMETVDMPFVKALIQNISTDVSEDLLYSLMLSQIPRQVMQGEDEPADGVRLPKSLFGA LPGNRSAVRLAITVLDIGAGNVFKGPKLLEDKGSSVLNNRMVGLSVGQMHATGLSEPVEI TFSHERQPPNVILTCVFWDMAKGDWDSHGCSTVPGDGRTVCRCDHLTFFALLLRPILDLA TAQTLTRISQAGSAVSMIFLAFTMVLYVAFRFSLQRFKSEDAPKIHMALSISLFLLNLTF LINVGSSSQGPPASCWVRAAIFHYFLLCVFTWMGLEAFHLYLLAIRVFNTYFGHYFLKLS LLAWGLPVLVVIGAGSSNSYGVYTIRDQENRTSLELCWFQKEPALYATVHGYFLVTFLFG AVVLALVAWKIFTLPSVTAGKGQGPTWKSVLTVLGLSSLVGMTWGLAVLTPLGLSTIYVF TLLNSLQGLFIFCWFIILYFPTQSTTASSSGTARLDQAHSVSQE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Orphan receptor that regulates migration of lymphatic endothelial cells via the small GTPases RhoA and CDC42. Regulates B-cell development. Seems to signal through G-alpha(q)-proteins.
基因功能參考文獻：
1. Results show that G protein-coupled receptor 97 protein (Gpr97) plays an important role in the development of experimental autoimmune encephalomyelitis (EAE) and may have a therapeutic potential for the treatment of central nervous system (CNS) autoimmunity. PMID: 29860267
2. Our findings imply that Gpr97 might not be required for the development of airway inflammation in OVA-induced allergic asthma in mice. PMID: 26132811
3. The GPR92 is expressed in the majority of T1R1-positive taste cells. PMID: 23436159
4. Gpr97 deficiency results in an extensive reduction in B220(+) lymphocytes in mice. PMID: 24113187
5. a possible role of GPR97 in lymphatic remodeling PMID: 24178298
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亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
組織特異性：

Specifically expressed in intestinal lymphatic endothelium.
數據庫鏈接：

KEGG: mmu:54672

STRING: 10090.ENSMUSP00000051079

UniGene: Mm.27995