Recombinant Mouse Opalin (Opalin)

in vitro E.coli expression system

中文名稱：

小鼠Opalin重組蛋白
貨號：

CSB-CF745364MO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Opalin
Uniprot No.：

Q7M750
別名：

Opalin; Tmem10; Opalin; Oligodendrocytic myelin paranodal and inner loop protein; Transmembrane protein 10
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-143
氨基酸序列

MSFSLNFTLPSNTTSSPVVTSAKATDCGPSIGLAAGIPSLLATALLVALLFTLIQRRRTI DDEPVEETEIPCEISELYDNPKISENPRRSPTHEMNPRGSQEGHIYVKTVSGSEEPLPDT YRPPEELERRRGLWWLVPSLSLE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
基因功能參考文獻：
1. study demonstrates that Tmem10 can be used as a specific marker for myelinating oligodendrocytes and perhaps for the evaluation of myelination diseases, such as multiple sclerosis PMID: 24391449
2. Together, our results demonstrate that Tmem10 is a novel marker for in vitro generated oligodendrocytes. PMID: 18439243
3. highly sialylglycosylated Opalin has a role in an intermembranous function of the myelin paranodal loops in the central nervous system PMID: 18490449
4. Tmem10 plays a possible role in oligodendrocyte differentiation and myelination of the central nervous system. PMID: 18571792
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
組織特異性：

Expressed specifically in oligodendrocytes of the brain.
數據庫鏈接：

KEGG: mmu:226115

STRING: 10090.ENSMUSP00000084422

UniGene: Mm.54119