Recombinant Mouse Metal transporter CNNM4 (Cnnm4)

in vitro E.coli expression system

中文名稱：

Recombinant Mouse Metal transporter CNNM4(Cnnm4)
貨號：

CSB-CF734761MO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Cnnm4
Uniprot No.：

Q69ZF7
別名：

Cnnm4; Acdp4; Kiaa1592; Metal transporter CNNM4; Ancient conserved domain-containing protein 4; mACDP4; Cyclin-M4
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-771
氨基酸序列

MAPGGGGGRRDGWPARGRLLLAALLLLWTRAASGQSSPQQSVILGMRLASCNKSCGMNPD GIIFVSEGSTVNLRLYGHSLGDISSNLISFTEVDDAEAVHNSTNCLELTKDLVVQRLVNV SRGNTSGMLVVITKFLRRSENMKLYALCTRPRADGPWTRWTDKDSLLFMVEEHGRFLPLW LHILLVMVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERKYARKIEPIRRKGNYLL CSLLLGNVLVNTSLTILLDNLIGSGIMAVASSTIGIVIFGEILPQALCSRHGLAVGANTI VLTKVFMLLTFPLSFPISKLLDFVLGQEIRTVYNREKLMEMLKVTEPYNDLVKEELNMIQ GALELRTKTVEDIMTQLHDCFMIRSDAILDFNTMSEIMESGYTRIPVFEDEQSNIVDILY VKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGE GDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRTRKRVSVKNKRDFSAFKDTDNELK VKISPQLLLAAHRFLATEVPQFSPSLMSEKILLRLLKYPDVIQELRFNEHNRYCVRHYLY TRNKPADCFVLILQGKVEVEAGKENMKFETGAFSYYGTMALSVAPPDRSPALPTPLSRSA SLSYPDRNTDLTSTSLAGSNQFGSCILGQYVSDFSVRALTDLQYIKITRQQYQNGLMASR MDNSPQPTFDGCATCSENFMERPELPPVDETTTLLNERNSLLHRASEEETI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions. May play a role in biomineralization and retinal function.
基因功能參考文獻：
1. These results suggest a new role of CNNM4 in sperm Ca(2+) homeostasis. PMID: 27006114
2. these results indicate that CNNM4-dependent Mg(2+) efflux suppresses tumor progression by regulating energy metabolism. PMID: 25347473
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

ACDP family
組織特異性：

Cornea, retina, teeth (at protein level). In the retina it is predominantly localized to the outer plexiform layer, inner plexiform layer and ganglion cell layer. In the tooth strongest expression is observed in the cell body of the ameloblasts. Expressed
數據庫鏈接：

KEGG: mmu:94220

STRING: 10090.ENSMUSP00000121317

UniGene: Mm.422638