Recombinant Mouse G-protein coupled receptor 6 (Gpr6)

in vitro E.coli expression system

中文名稱：

小鼠Gpr6重組蛋白
貨號：

CSB-CF757875MO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Gpr6
Uniprot No.：

Q6YNI2
別名：

Gpr6; Gm233; G-protein coupled receptor 6; Sphingosine 1-phosphate receptor GPR6
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-363
氨基酸序列

MNASAAALNESQVVAVAAEGAAAAATAAGAPDTGEWGPPAASAALGGGGGPNGSLELSSQ LPAGPSGLLLSAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADL LAGCGLILHFVFQYVVPSETVSLLMVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSR RTLLGVHLLLAATWTVSLGLGLLPVLGWNCLADRTSCSVVRPLTRSHVALLSTSFFVVFG IMLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYC VVGSQEDPAIYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLFCGCFQSKVPFRSRSP SEV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons.
基因功能參考文獻：
1. Gpr6 deficiency causes an interesting behavioural phenotype in the form of enhanced motor activity combined with reduced abnormal involuntary movements. PMID: 24747358
2. identification, characterization and cloning; identified sphingosine-1-phosphate as a high-affinity ligand PMID: 14592418
3. Gpr6 is the first striatopallidal neuron-specific genetic regulator of instrumental conditioning in a mammal. PMID: 17934457
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Note=Highly expressed and localized along the cytoplasmic membrane as well as in a perinuclear compartment.
蛋白家族：

G-protein coupled receptor 1 family
組織特異性：

Mainly expressed in the brain. Selectively expressed in striatopallidal neurons in the striatum.
數據庫鏈接：

KEGG: mmu:140741

STRING: 10090.ENSMUSP00000057323

UniGene: Mm.290693