Recombinant Mouse E3 ubiquitin-protein ligase RNF13 (Rnf13)
產(chǎn)品詳情
-
基因名：Rnf13
-
Uniprot No.：
-
別名：Rnf13; Rzf; E3 ubiquitin-protein ligase RNF13; RING finger protein 13; RING-type E3 ubiquitin transferase RNF13
-
種屬：Mus musculus (Mouse)
-
蛋白長度：Full Length of Mature Protein
-
表達(dá)區(qū)域：35-381
-
氨基酸序列DILAYNFENASQTFEDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPLKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIDTLKKIDIPSVFIGESSANSLKDEFTYEKGGHIILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRLRKDQLKKLPVHKFKKGDEYDVCAICLEEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQEENQVSEHTPLLPPSASARTQSFGSLSESHSHHNMTESSDYEDDDNEETDSSDADNEITDHSVVVQLQPNGEQDYNIANTV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering. -
蛋白標(biāo)簽：N-terminal 10xHis-tagged
-
產(chǎn)品提供形式：Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
緩沖液：Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
-
儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
-
保質(zhì)期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
-
注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
Datasheet & COA：Please contact us to get it.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA.
-
基因功能參考文獻(xiàn)：
- host RNF13 affects the concentration of GM-CSF in tumor-bearing lungs PMID: 26197965
- These results indicate that RNF13 deficiency promotes skeletal muscle regeneration via the effects on satellite cell niche mediated by IL-4 and IL-6. PMID: 24563216
- RNF13 is involved in the regulation of the SNARE complex, which thereby controls synaptic function. PMID: 22890573
-
亞細(xì)胞定位：Endoplasmic reticulum membrane. Late endosome membrane; Single-pass membrane protein. Lysosome membrane. Cytoplasm, cytosol. Nucleus inner membrane. Note=The mature protein is subjected to extensive proteolysis that leads to the shedding of the ectodomain into the lumen of vesicles and the release of the C-terminal fragment into the cytosol. Not detected in early endosomes. Treatment of the cells with either PMA or ionomycin stabilizes the full-length protein which relocalizes to recycling endosomes and to the inner nuclear membrane.
-
組織特異性：Expressed in the brain, heart, kidney, liver and spleen. Higher expression in adult tissues compared to the embryonic counterparts.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
Recombinant Macaca fascicularis zymogen granule protein 16 homolog B (ZG16B) (Active)
Express system: Mammalian cell
Species: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
-
Recombinant Human Alkaline phosphatase, germ cell type (ALPG) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Macaca fascicularis C-type lectin domain family 4 member C(CLEC4C), partial (Active)
Express system: Mammalian cell
Species: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
-
Recombinant Human Kidney-associated antigen 1(KAAG1) (Active)
Express system: Baculovirus
Species: Homo sapiens (Human)
-
Recombinant Human Tyrosine-protein kinase receptor UFO(AXL),partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
