Recombinant Mouse Cytochrome b561 (Cyb561)

in vitro E.coli expression system

中文名稱：

Recombinant Mouse Cytochrome b561(Cyb561)
貨號：

CSB-CF726669MO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Cyb561
Uniprot No.：

Q60720
別名：

Cyb561; Mcyt; Transmembrane ascorbate-dependent reductase CYB561; Chromaffin granule Cyt b561; CGCytb; Cytochrome b-561; Cytochrome b561
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-250
氨基酸序列

MEHSSASVPAALPYYVAFSQLLGLTVVAVTGAWLGLYRGGIAWESSLQFNVHPLCMVIGM IFLQGDALLVYRVFRREAKRTTKILHGLLHVFAFIIALVGLVAVFDYHKKKGYADLYSLH SWCGILVFVLYFVQWLVGFSFFLFPGASFSLRSRYRPQHIFFGATIFLFSVGTALLGLKE ALLFKLGSKYSTFEPEGVLANVLGLLLVCFGVVVLYILAQADWKRPSQAEEQALSMDFKT LTEGDSPSPQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles (Probable). It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes.
基因功能參考文獻：
1. dihydrolipoic acid (DHLA)-dependent reduction of these two Cyt-b561 proteins PMID: 22526465
2. expression of Cytochrome b561, is androgen regulated in the context of CaP cells and its increased expression in castration recurrent prostate cancer reflects increased androgen receptor signaling in tumor cells PMID: 21045261
3. Data show that four members of the b561 family of predicted ferric reductases: mouse cytochrome b561, human duodenal cytochrome b, and mouse stromal cell-derived receptor 2, have ferric reductase activity. PMID: 14499595
亞細胞定位：

Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Multi-pass membrane protein.
組織特異性：

Abundantly distributed in a number of neuroendocrine tissues.
數據庫鏈接：

KEGG: mmu:13056

STRING: 10090.ENSMUSP00000019734

UniGene: Mm.149403