Recombinant Innexin unc-7 (unc-7)

in vitro E.coli expression system

中文名稱：

秀麗隱桿線蟲unc-7重組蛋白
貨號：

CSB-CF312700CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

unc-7
Uniprot No.：

Q03412
別名：

unc-7; unc-12; unc-124; R07D5.1; Innexin unc-7; Uncoordinated protein 7
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區(qū)域：

1-522
氨基酸序列

MLGSSSNPEPPLLSRIIGVPPPPPPRAPTTALVLRVPTVDSPSKKKQQPDTRNKYQETAL RDKKTRTPLEKARHLDNLPSYQAQKLLDGSHQLRIDSHHVGSAGHGAGQGHGHKKEFGPA MILYYLASAFRALYPRLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFT DAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCIL WRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSC FSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLM HAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVT VCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRM ISTHAGELMSSELILALWQDFNNVDRSPTQFWDAEHGQGTID
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Structural component of the gap junctions. Required for coordinated locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt. Plays a role in regulating male mating behavior by positively regulating inhibitory neuronal signaling transduction between chemosensory and mechanosensory neurons, and thus ensuring spicule insertion attempts are confined to the hermaphrodite vulva during copulation.
基因功能參考文獻：
1. This study showed that isoform, which perturbs DOP-2 signaling in the PCB neuron and its electrical partner, hook neurons. PMID: 26156999
2. UNC-7 is localized perisynaptically throughout development and is required in presynaptic neurons to regulate active zone differentiation. PMID: 19386917
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
蛋白家族：

Pannexin family
組織特異性：

In hermaphrodites, expressed in all premotor and motor neurons, and in tail neurons. In males, expressed in the anal depressor, gubernacular erector, gubernacular retractor and anterior oblique muscles, SPC, PCA, PCB, HOA, ray, head ganglion and ventral c
數(shù)據(jù)庫鏈接：

STRING: 6239.R07D5.1a

UniGene: Cel.17909