Recombinant Drosophila melanogaster Protein catecholamines up (Catsup)

in vitro E.coli expression system

中文名稱：

Recombinant Drosophila melanogaster Protein catecholamines up(Catsup)
貨號(hào)：

CSB-CF893699DLU
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

基因名：

Catsup
Uniprot No.：

Q9V3A4
別名：

Catsup; CG10449; Protein catecholamines up
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-449
氨基酸序列

MAKQVADYQCSKLQLYQKLALVVILGAVLFSLPALCAGQGNPSFKYSREANENFDPQKAP RAEHHHHHDHDHDHGHHHHGHDHDHDHDHGHDHGHHHHGHDHDHDHDHGHHHHGHDERHT KAKPDLDMSTIWLHSIGSTLLISAAPFVLLYIIPLDNSEAMKPRLKVLLAFASGGLLGDA FLHLIPHATHPHSHGEHGHDHGHDHHHHHDGEEHEHGHSHDMSIGLWVLGGIIAFLSVEK LVRILKGGHGGHGHSHGAPKPKPVPAKKKSSDKEDSGDGDKPAKPAKIKSKKPEAEPEGE VEISGYLNLAADFAHNFTDGLAIGASYLAGNSIGIVTTITILLHEVPHEIGDFAILIKSG CSRRKAMLLQLVTALGALAGTALALLGAGGGDGSAPWVLPFTAGGFIYIATVSVLPELLE ESTKLKQSLKEIFALLTGVALMIVIAKFE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Negatively regulates tyrosine hydroxylase activity.
基因功能參考文獻(xiàn)：
1. Loss of Catsup function causes Notch to accumulate abnormally in the endoplasmic reticulum (ER) and Golgi compartments, resulting in impaired Notch signaling. In addition, Catsup mutant cells exhibit elevated ER stress, suggesting that impaired zinc homeostasis causes increased levels of misfolded proteins within the secretory compartment. PMID: 23785054
2. The results of this study concluded that Catsup regulates and links the dopamine synthesis and transport networks. PMID: 21985068
3. Catsup is a pleiotropic quantitative trait gene, but individual quantitative trait nucleotides do not have pleiotropic effects. Molecular population genetic analyses are consistent with balancing selection maintaining multiple functional polymorphisms. PMID: 16682353
4. Molecular polymorphisms in Catsup (Catecholamines up) are associated with variation in sleep. PMID: 19234472
亞細(xì)胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

ZIP transporter (TC 2.A.5) family, KE4/Catsup subfamily
數(shù)據(jù)庫(kù)鏈接：

KEGG: dme:Dmel_CG10449

STRING: 7227.FBpp0080687

UniGene: Dm.12530