Recombinant Drosophila melanogaster Octopamine receptor beta-2R (Octbeta2R)

in vitro E.coli expression system

中文名稱：

黑腹果蠅Octbeta2R重組蛋白
貨號：

CSB-CF683813DLU
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Octbeta2R
Uniprot No.：

Q4LBB9
別名：

Octbeta2R; Octbeta2; CG33976; Octopamine receptor beta-2R; DmOct-beta-12; DmOct-beta-2R
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

full length protein
表達區域：

1-536
氨基酸序列

MLLCDGLGPEPPRQRHRNRTSAARIRKRPKCCCGDGGSGNQAEQPGGIVSNPISYGQSLT TLARVTAAALTTAAMLHTTNALAATGSSSASNSSTGGIALPLGTATPATHELNATQPFGG SGLNFNESGAGLSDHHHHQQHNPDEDWLDNIVWVFKAFVMLLIIIAAICGNLLVIISVMR VRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWNSLDVYFSTAS ILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIFIGWYTTPQHQ QFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQEKQLMMRHGNAM LMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGIIMGTF ILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTL LCLFCNWWKDRHLPLDIDIRRSSLRYDQRAKSVYSESYLNSTTPSHRRQSQMVDNL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Autoreceptor for octopamine (OA), which is a neurotransmitter, neurohormone, and neuromodulator in invertebrates. Essential for ovulation and fertilization. During ovulation it mediates the OA-induced relaxation of the oviduct visceral muscles, by increasing cAMP levels and activating effectors such as calmodulin-dependent kinase II (CaMKII) and cAMP-dependent protein kinase A (PKA) pathways. Positively regulates synaptic growth; an action that is antagonized by Octbeta1R.
基因功能參考文獻：
1. These observations suggest that Octbeta2R have distinct signaling capacities in vivo and activate multiple signaling pathways to induce egg laying. PMID: 25099506
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family
組織特異性：

In the adult, expressed in the superior protocerebrum and the optic lobe medulla of the central nervous system, nurse cells of egg chambers in the ovary at oogenic stages 1-10, and spermatogonia and spermatocytes in the testis. Expressed in the oviduct ep
數據庫鏈接：

KEGG: dme:Dmel_CG33976

STRING: 7227.FBpp0303153

UniGene: Dm.29778