Recombinant Dog Vasopressin V2 receptor (AVPR2)

in vitro E.coli expression system

中文名稱：

Recombinant Dog Vasopressin V2 receptor(AVPR2)
貨號：

CSB-CF002470DO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

AVPR2
Uniprot No.：

O77808
別名：

AVPR2; V2R; Vasopressin V2 receptor; AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor
種屬：

Canis familiaris (Dog) (Canis lupus familiaris)
蛋白長度：

full length protein
表達區域：

1-370
氨基酸序列

MLLASTTSAVPRTLSPPTPAGNGSRELLDTRDPLLVQAELALLSTVFVAVALSNGLVLGA LARRVRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMV GMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLILSLPQLFIFAQR DVGNGSGVLDCWAHFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHSSLVPGPA ERAGGCRGGHRTGSPSEGARVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPQAP LEGAPFVLLMLLASLNSCTNPWIYAFFSSSVSSELRSLFCWARSRAPPSLGPQEESCATA SSFLAKDTSS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.
基因功能參考文獻：
1. vasopressin receptor type 2 signaling is controlled by retromer and arrestin in a noncanonical regulatory pathway PMID: 23935101
2. ectopic expression of gastric-inhibitory polypeptide and vasopressin(2) receptor proteins in tumorous zona fasciculata tissue may play a role in the pathogenesis of canine cortisol-secreting adrenocortical tumors PMID: 20399066
3. a C-terminal region of the V2R important for calmodulin interaction is also important in modulation of V2R elevation of intracellular Ca2 PMID: 15319442
4. X-linked nephrogenic diabetes insipidus is caused by mutations in the gene encoding the vasopressin V2 receptor PMID: 16006591
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily
數據庫鏈接：

KEGG: cfa:403804

STRING: 9615.ENSCAFP00000028678

UniGene: Cfa.3666