Recombinant Bovine Neuronal acetylcholine receptor subunit beta-4 (CHRNB4)

in vitro E.coli expression system

中文名稱：

Recombinant Bovine Neuronal acetylcholine receptor subunit beta-4(CHRNB4)
貨號：

CSB-CF819361BO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

CHRNB4
Uniprot No.：

Q8SPU6
別名：

CHRNB4; ACRB4; Neuronal acetylcholine receptor subunit beta-4
種屬：

Bos taurus (Bovine)
蛋白長度：

Full Length of Mature Protein
表達區域：

20-496
氨基酸序列

DCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIQLQLSLAQLISVNEREQIMTTNI WLKQEWTDYRLAWNSSRYEGVNILRIPANRVWLPDIVLYNNADGSYEVSLYTNVVVRSNG SVMWLPPAICKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDMVLKMPTASMDDFTPSG EWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLITSLAILVFYLPSD CGEKMTLCISVLLALTVFLLLISKIVPPTSLNVPLIGKYLMFTMVLVTFSIVTSVCVLNV HHRSPSTHTMAPWVKRCFLHKLPTFLFIKRPRQQPSRAPQSSLARLTKSEATTTTTLAMG PTSSSNLYGNSMYFVNPGLAAPKSPVASDSAGIPRDFRLRSSGRFRQDVQEALEGVSFIA QHMKSDDLDQSVIEDWKYVAMVVDRLFLWVFVVVCVLGTVGLFLPPLFQTHTPSEEP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
基因功能參考文獻：
1. Data show that a basic residue at position 210 of the beta4 subunit slightly decreases alpha3beta4 receptor expression. PMID: 21420959
2. Bovine chromaffin cells express nicotinic alpha3beta4 acetylcholine receptors PMID: 12438106
3. Bovine chromaffin cells have an alpha3alpha7beta4 nicotinic receptor PMID: 12438113
亞細胞定位：

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
蛋白家族：

Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Beta-4/CHRNB4 sub-subfamily
數據庫鏈接：

KEGG: bta:282181

STRING: 9913.ENSBTAP00000048228

UniGene: Bt.9978