Recombinant Arabidopsis thaliana Fatty acid amide hydrolase (FAAH)

in vitro E.coli expression system

中文名稱：

擬南芥FAAH重組蛋白
貨號：

CSB-CF007938DOA
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

FAAH
Uniprot No.：

Q7XJJ7
別名：

FAAH; At5g64440; T12B11.3; Fatty acid amide hydrolase; AtFAAH; N-acylethanolamine amidohydrolase
種屬：

Arabidopsis thaliana (Mouse-ear cress)
蛋白長度：

full length protein
表達區域：

1-607
氨基酸序列

MGKYQVMKRASEVDLSTVKYKAETMKAPHLTGLSFKLFVNLLEAPLIGSLIVDYLKKDNG MTKIFRNTVIPEEPMFRPEFPSQEPEHDVVIVGEDESPIDRLETALKCLPQYDPSRSLHA DPVSSFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQ AEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRS CGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGT DGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGS SSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSN NHGCKVVEIVVPELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFS ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMR FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF YDILNTN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the hydrolysis of bioactive endogenous fatty acid amides to their corresponding acids. The hydrolysis of endogenous amidated lipids terminates their participation as lipid mediators in various signaling systems (Probable). Converts a wide range of N-acylethanolamines (NAEs) to their corresponding free fatty acids and ethanolamine. Can use oleamide as substrate, but not indole-3-acetamide, 1-naphtalene-acetamide, nicotinic acid amide or L-asparagine. Can use 2-arachidonylglycerol as substrate. Participates in the regulation of plant growth. Hydrolyzes N-dodecanoylethanolamine, which is has a growth inhibitory effect on seedling growth. Involved in plant defense signaling. Involved in abscisic acid (ABA) signaling through mechanisms that are independent of the catalytic activity. Involved in the regulation of flowering time. Catalyzes the hydrolysis of N-acyl L-homoserine lactones (AHLs), which are a class of signaling molecules produced by bacteria for quorum sensing. Accumulation of L-homoserine appears to encourage plant growth at low concentrations by stimulating transpiration, but higher concentrations inhibit growth by stimulating ethylene production.
基因功能參考文獻：
1. our study demonstrates the feasibility of using an unbiased chemical genetic approach to identify new pharmacological tools for manipulating FAAH- and NAE-mediated physiological processes in plants. PMID: 28112243
2. AtFAAH is one, but not the only, modulator of endogenous N-Acylethanolamines (NAE) levels in plants, and that NAE depletion likely participates in the regulation of plant growth [fatty acid amide hydrolase] [AtFAAH] PMID: 16880402
3. Overexpression of AtFAAH inhibits innate immunity against Pseudomonas syringae in Arabidopsis, and plants had lower amounts of jasmonic acid, abscisic acid, and salicylic acid. PMID: 18643971
4. AtFAAH influences plant growth and interacts with ABA signaling and plant defense through distinctly different mechanisms PMID: 19801664
亞細胞定位：

Endoplasmic reticulum membrane. Cell membrane.
蛋白家族：

Amidase family
組織特異性：

Expressed in roots, leaves and flowers. Expressed in seedlings, flowers, roots, siliques, seeds and leaves.
數據庫鏈接：

KEGG: ath:AT5G64440

STRING: 3702.AT5G64440.1

UniGene: At.19619