Recombinant Arabidopsis thaliana ATP-dependent zinc metalloprotease FTSH 4, mitochondrial (FTSH4)

in vitro E.coli expression system

中文名稱：

擬南芥FTSH4重組蛋白
貨號：

CSB-CF529299DOA
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

FTSH4
Uniprot No.：

O80983
別名：

FTSH4; At2g26140; T19L18.5; ATP-dependent zinc metalloprotease FTSH 4, mitochondrial; AtFTSH4
種屬：

Arabidopsis thaliana (Mouse-ear cress)
蛋白長度：

Full Length of Mature Protein
表達區域：

29-717
氨基酸序列

SSFPRVGVTGAVGGGGASLPRTRFQSSYVGSFARRVRDREEVNEVAHLRELIRRNDPEAV IRMFESQPSLHANASALSEYIKALVKVDRLDQSELVRTLQRGIAGVAREEETFGGLGAFR NVGKPTKDGVLGTASAPIHTISTERTHFKEQLWSTIRTIGVGFLLISGIGALIEDRGIGK GLGLHEEVQPSMDSSTKFSDVKGVDEAKAELEEIVHYLRDPKRFTRLGGKLPKGVLLVGP PGTGKTMLARAIAGEAGVPFFSCSGSEFEEMFVGVGARRVRDLFSAAKKCSPCIIFIDEI DAIGGSRNPKDQQYMKMTLNQMLVELDGFKQNEGIIVVAATNFPESLDKALVRPGRFDRH IVVPNPDVEGRRQILESHMSKVLKAEDVDLMIIARGTPGFSGADLANLVNVAALKAAMDG SKDVTMSDLEFAKDRIMMGSERKSAVISDESRKLTAFHEGGHALVAIHTEGALPVHKATI VPRGMALGMVSQLPDKDETSISRKQMLARLDVCMGGRVAEELIFGESEVTSGASSDLEQA TKLARAMVTKFGMSKEVGLVAHNYDDNGKSMSTETRLLIESEVKQLLEKAYNNAKTILTV YNKELHALANALLQHETLSGKQIKELLTDLNSPLLQKRQEVVTKQSNPVPPSTPSSASSA AAAAAAAAAAAAAAAATAATKGKDMAPVS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Probable ATP-dependent zinc metallopeptidase. Involved in the assembly and/or stability of the complex V of the mitochondrial oxidative phosphorylation system.
基因功能參考文獻：
1. Growth arrest in the ftsh4-1 mutant is caused by cell cycle dysregulation in addition to the loss of stem cell identity. PMID: 29538317
2. Data revealed several putative targets of FTSH4, novel (mitochondrial pyruvate carrier 4 (MPC4) and Pam18-2) and known (Tim17-2) substrates of this protease. Furthermore, These results demonstrate that FTSH4 degrades damaged proteins by oxidative stress in mitochondria and provide new insights into the function of FTSH4 in the maintenance of plant mitochondrial proteome. PMID: 29156584
3. Maintaining mitochondria functionality within the The shoot apical meristem, dependent on AtFTSH4, is vital to preserving stem cell activity throughout development PMID: 27321362
4. Loss of function of transcription factor WRKY75 in the mitochondrial protease ftsh4-4 mutants decreased the levels of salicylic acid (SA) and reversed the senescence phenotype. PMID: 28250067
5. the loss of FtsH4 regulates development and architecture by mediating the peroxidase-dependent interplay between hydrogen peroxide and auxin homeostasis PMID: 25763704
6. mitochondrial FtSH4 gene-mediated peroxidase accumulation regulates arabidopsis architecture PMID: 24482432
7. processing of AtFtsH4 precursor by mitochondrial processing peptidase PMID: 22986791
8. AtFtsH4 is an exclusively mitochondrial protein while AtFtsH11 is found in both chloroplasts and mitochondria. PMID: 16247555
9. Lack of AtFtsH4 results in impairment of organelle development and Arabidopsis leaf morphology under short-day conditions. PMID: 19453455
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亞細胞定位：

Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
蛋白家族：

AAA ATPase family; Peptidase M41 family
數據庫鏈接：

KEGG: ath:AT2G26140

STRING: 3702.AT2G26140.1

UniGene: At.23415