Recombinant Xenopus laevis Protein Wnt-3a (wnt3a)

中文名稱：

有爪蟾蜍wnt3a重組蛋白
貨號：

CSB-YP026136XBE
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍wnt3a重組蛋白
貨號：

CSB-EP026136XBE
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍wnt3a重組蛋白
貨號：

CSB-EP026136XBE-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍wnt3a重組蛋白
貨號：

CSB-BP026136XBE
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍wnt3a重組蛋白
貨號：

CSB-MP026136XBE
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

wnt3a
Uniprot No.：

P31285
別名：

wnt3a; Protein Wnt-3a; XWnt-3a
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

Full Length of Mature Protein
表達區域：

19-352
氨基酸序列

TY PIWWSLAVGQ QYSSLGTQPI PCGTIPGLVA KQMRFCRNYM EIMPSVAEGV KIGIQECQHQ FRGRRWNCTT VNDNLAIFGP VLDKATRESA FVHAIASAGV AFAVTRSCAE GSATICGCDT HHKGPPGEGW KWGGCSEDMD FGSMVSREFA DARENRPDAR SAMNRHNNEA GRTSILDHRH LKCKCHGLSG SCEVKTCWWS QPDFRVIGDY LKDKYDSASE MVVEKHRESR GWVETLRPKY TFFKPPIERD LIYYESSPNF CEPNPETGSF GTRDRECNVT SHGIDGCDLL CCGRGQNTRT EKRKEKCHCI FHWCCYVSCQ ECMRVYDVHT CK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube.
基因功能參考文獻：
1. Sulf1 does not affect Wnt3a-mediated activation of canonical Wnt signaling. PMID: 25681501
2. Wnt3a protein alone is sufficient to rescue the severe loss of inner ear structures resulting from dorsal but not ventral half ablations. PMID: 24500889
3. hindbrain-repressive Wnt3a/Meis3/Tsh1 circuit promotes neuronal differentiation and coordinates tissue maturation PMID: 22399680
4. Wnt3a thus acts downstream of FAK to balance anterior-posterior cell fate specification in the developing neural plate PMID: 21551070
5. Data suggest a new model for neural anteroposterior patterning, in which Wnt3a from the paraxial mesoderm induces posterior cell fates via direct activation of a crucial transcription factor in the overlying neural plate. PMID: 20356957
6. Wnt3A secretion from tectal cells along with ephrin-B1 signaling are specifically responsible for enhanced neural responses in the developing optic tectum. PMID: 20346764
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亞細胞定位：

Secreted, extracellular space, extracellular matrix. Secreted.
蛋白家族：

Wnt family
組織特異性：

At neurula in anterior neural fold; at tailbud in dorsal midline of midbrain.
數據庫鏈接：

KEGG: xla:378679

UniGene: Xl.880