Recombinant Xenopus laevis E3 SUMO-protein ligase NSE2 (nsmce2)

中文名稱：

有爪蟾蜍nsmce2重組蛋白
貨號：

CSB-YP773843XBE
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍nsmce2重組蛋白
貨號：

CSB-EP773843XBE
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍nsmce2重組蛋白
貨號：

CSB-EP773843XBE-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍nsmce2重組蛋白
貨號：

CSB-BP773843XBE
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍nsmce2重組蛋白
貨號：

CSB-MP773843XBE
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

nsmce2
Uniprot No.：

Q7ZXH2
別名：

nsmce2; mms21; E3 SUMO-protein ligase NSE2; EC 2.3.2.-; E3 SUMO-protein transferase NSE2; MMS21 homolog; Non-structural maintenance of chromosomes element 2 homolog; Non-SMC element 2 homolog
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

full length protein
表達區域：

1-238
氨基酸序列

MSGRSAPVVS FSSVDNSLSS LKNCQGYLHT GMDITVSVAL DLLETGCEST EVDAMESVML EYSAMERDLK QYIHAVEETV QKLRREQMEQ VPDLQSLVQE KYATIQKKND DEDLKKNDRF VQFKDQLREM RKQMGEKEEG DAAFENVDED IAVLPSQQNL TCPITQMEMT NPVKNKVCGH TYEKEAIERM IQDRHQKKKR VKCPKVGCVH SDMQISDLVP DTALKRTIDI LNKQKGRH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression.
亞細胞定位：

Nucleus. Chromosome, telomere.
蛋白家族：

NSE2 family
數據庫鏈接：

KEGG: xla:379272

UniGene: Xl.15557