Recombinant Vaccinia virus Interferon antagonist C7L (VACWR021)

中文名稱：

Recombinant Vaccinia virus Interferon antagonist C7L (VACWR021)
貨號：

CSB-YP301573VAI
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Vaccinia virus Interferon antagonist C7L (VACWR021)
貨號：

CSB-EP301573VAI
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Vaccinia virus Interferon antagonist C7L (VACWR021)
貨號：

CSB-EP301573VAI-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Vaccinia virus Interferon antagonist C7L (VACWR021)
貨號：

CSB-BP301573VAI
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Vaccinia virus Interferon antagonist C7L (VACWR021)
貨號：

CSB-MP301573VAI
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

VACWR021
Uniprot No.：

P68600
別名：

VACWR021; C7LInterferon antagonist C7; Host range protein 2
種屬：

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
蛋白長度：

full length protein
表達區域：

1-150
氨基酸序列

MGIQHEFDII INGDIALRNL QLHKGDNYGC KLKIISNDYK KLKFRFIIRP DWSEIDEVKG LTVFANNYAV KVNKVDDTFY YVIYEAVIHL YNKKTEILIY SDDENELFKH YYPYISLNMI SKKYKVKEEN YSSPYIEHPL IPYRDYESMD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Inhibits antiviral activity induced by type I interferons. Does not block signal transduction of IFN, but is important to counteract the host antiviral state induced by a pre-treatment with IFN.
基因功能參考文獻：
1. Authors generated recombinant vaccinia viruses carrying deletion mutants of the C7L gene and found that the N-terminus is essential for host range function of C7L. PMID: 23001690
2. K1L and C7L antagonize IRF1-induced antiviral activities and that the host modulation function of C7L is evolutionally conserved in all poxviruses that can readily replicate in tissue-cultured mammalian cells. PMID: 22345458
3. Viral K1L and C7L prevent eIF2alpha phosphorylation in vaccinia virus infection of human and murine cell lines. PMID: 19846675
4. Antagonizes antiviral activities induced by type I interferons. PMID: 19656868
蛋白家族：

Poxviridae C7 protein family
數據庫鏈接：

KEGG: vg:3707636