Recombinant Streptococcus pneumoniae DNA-entry nuclease (endA), partial

中文名稱：

肺炎鏈球菌endA重組蛋白
貨號：

CSB-YP358413SMP
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

肺炎鏈球菌endA重組蛋白
貨號：

CSB-EP358413SMP
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

肺炎鏈球菌endA重組蛋白
貨號：

CSB-EP358413SMP-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

肺炎鏈球菌endA重組蛋白
貨號：

CSB-BP358413SMP
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

肺炎鏈球菌endA重組蛋白
貨號：

CSB-MP358413SMP
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

endA
Uniprot No.：

P0A3S4
別名：

endA; spr1779DNA-entry nuclease; Competence-specific nuclease; EC 3.1.30.-
種屬：

Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed.
基因功能參考文獻：
1. The EndA nuclease, a constitutively expressed virulence factor, is recruited during competence to play the key role of converting dsDNA into ssDNA for uptake. PMID: 24039578
2. Data indicaate that the competence-independent activity of endonuclease EndA is responsible for the rapid degradation of DNA and neutrophil extracellular traps (NETs) and is required for the full virulence during lung infection. PMID: 23936195
3. EndA allows pneumococci to degrade the DNA scaffold of neutrophil extracellular traps and escape. PMID: 16488875
亞細胞定位：

Cell membrane; Single-pass membrane protein.
蛋白家族：

DNA/RNA non-specific endonuclease family
數據庫鏈接：

KEGG: spr:spr1779

STRING: 171101.spr1779