Recombinant Sheep Natriuretic peptides B (NPPB)

中文名稱：

綿羊NPPB重組蛋白
貨號：

CSB-YP016021SH
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

綿羊NPPB重組蛋白
貨號：

CSB-EP016021SH
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

綿羊NPPB重組蛋白
貨號：

CSB-EP016021SH-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

綿羊NPPB重組蛋白
貨號：

CSB-BP016021SH
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

綿羊NPPB重組蛋白
貨號：

CSB-MP016021SH
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

NPPB
Uniprot No.：

O46541
別名：

NPPBNatriuretic peptides B; Gamma-brain natriuretic peptide) [Cleaved into: Brain natriuretic peptide 29; BNP-29); Brain natriuretic peptide 26; BNP-26)]
種屬：

Ovis aries (Sheep)
蛋白長度：

Full Length of Mature Protein
表達(dá)區(qū)域：

27-129
氨基酸序列

HPLG GPGSASELPG LQELLDRLRD RVSELQAEQL RVEPLQQGQG LEETWDSPAA APAGFLGPHH SLLQALRGPK MMRDSGCFGR RLDRIGSLSG LGCNVLRRY
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3.
基因功能參考文獻(xiàn)：
1. ANP and BNP plasma concentrations are sourced from a single organ (the heart) and are subject to substantial extraction across most tissue beds in experimental heart failure. PMID: 16095755
2. In a model of congenital cardiac defect with increased pulmonary blood flow, soluble guanylate cyclase alpha (sGCalpha) was greater at 2 & 4 weeks, & sGCbeta & phosphodiesterase 5 (PDE5) were greater at 4 weeks; plasma BNP increased. PMID: 17902145
亞細(xì)胞定位：

Secreted.
蛋白家族：

Natriuretic peptide family
數(shù)據(jù)庫鏈接：

KEGG: oas:100294642

UniGene: Oar.19888