Recombinant Schizosaccharomyces pombe Mei4-dependent protein 2 (mde2)

中文名稱：

龐貝裂殖酵母mde2重組蛋白
貨號：

CSB-YP311244SXV
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

龐貝裂殖酵母mde2重組蛋白
貨號：

CSB-EP311244SXV
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

龐貝裂殖酵母mde2重組蛋白
貨號：

CSB-EP311244SXV-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

龐貝裂殖酵母mde2重組蛋白
貨號：

CSB-BP311244SXV
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

龐貝裂殖酵母mde2重組蛋白
貨號：

CSB-MP311244SXV
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

mde2
Uniprot No.：

P87309
別名：

mde2; SPBC31F10.08Mei4-dependent protein 2
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長度：

full length protein
表達區域：

1-278
氨基酸序列

MENYTKSTTM CGKRKPTFEI YRESDFSKIT NQGTVTAFDI ISNKETFSES KQLKKAKSRN VTLVDKNTKA DKRYKSEKLS DYLLNQEHHK NSPKIINDVL VIGKSDGLIN SFPLSQNYIS SSESQTSSGN VDIIGNDNSH ASPYLPKFEL KSQSQSNHSN VVKNQPIKLC KKTEGGTNLD HNKSINGAVK SGTSKSANKD RIYVFYEDEE VMEYRYIFGS RMQTKNHDIN ANNKRKIFYQ NSFSNFHLLH KIIQPNYEPA SAEERKLCIE ILDEVLQY
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Required for the formation of meiotic double-strand breaks and for the segregation of homologous centromeres during meiosis I. Interacts with the SFT and DSBC complexes, two subcomplexes involved in the formation of meiotic double-strand breaks. Stabilizes the SFT subcomplex on DSB sites and recruits the DSBC subcomplex onto DSB sites.
基因功能參考文獻：
1. Mde2, whose expression is strictly regulated by the replication checkpoint, interacts with Rec15 to stabilize the SFT subcomplex and further binds Rec14 in DNA double-strand breaks. PMID: 22841486
2. mde2 is required for formation of the double-strand breaks necessary for meiotic recombination. PMID: 16169489
數據庫鏈接：

KEGG: spo:SPBC31F10.08

STRING: 4896.SPBC31F10.08.1