Recombinant Schizosaccharomyces pombe Eukaryotic translation initiation factor 3 subunit E (int6), partial

中文名稱：

龐貝裂殖酵母int6重組蛋白
貨號：

CSB-YP007534SXV
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

龐貝裂殖酵母int6重組蛋白
貨號：

CSB-EP007534SXV
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

龐貝裂殖酵母int6重組蛋白
貨號：

CSB-EP007534SXV-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

龐貝裂殖酵母int6重組蛋白
貨號：

CSB-BP007534SXV
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

龐貝裂殖酵母int6重組蛋白
貨號：

CSB-MP007534SXV
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

int6
Uniprot No.：

O94513
別名：

int6; eif3e; yin6; SPBC646.09c; Eukaryotic translation initiation factor 3 subunit E; eIF3e
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長度：

Partial
表達區域：

1-501
氨基酸序列

MGSELKSTSP LAVKYDLSQK IMQHLDRHLI FPLLEFLSLR QTHDPKELLQ AKYDLLKDTN MTDYVANLWT NLHGGHTDED MANAFAEKRR SVLQELSELE EEVQGILGVL ENPDLIAALR QDKGQNLQHL QEHYNITPER IAVLYKFAQF QYNCGNYGGA SDLLYHFRAF SKDPELNASA TWGKFASEIL TVDWDGAMEE LGKLREMVDS KSFKDSAVQL RNRTWLLHWS LFPLFNHANG CDTLCDLFFY TPYLNTIQTS CPWLLRYLTV AVVTNQNNAN QKPRNPRQSY QRRMRDLVRI ISQENYEYSD PVTSFISALY TEVDFEKAQH CLRECEEVLK TDFFLVSLCD HFLEGARKLL AEAYCRIHSV ISVDVLANKL EMDSAQLIQL VENRNNPSVA AASNVAADQS TEDESIESTS TNVVADDLIT EAETATEAEE PEPEVQFGFK AKLDGESIII EHPTYSAFQQ IIDRTKSLSF ESQNLEQSLA KSISELKHAT V
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation (Potential). Required for maintaining the basal level of atf1 and for transcriptional activation of core environmental stress response genes (CESR genes) in response to histidine starvation. May positively regulate proteasome activity. Required for nuclear localization of the proteasome subunit rpn501/rpn502.
基因功能參考文獻：
1. A transcript-specific eIF3 complex mediates global translational control of energy metabolism. PMID: 27477275
2. Results suggest that Cdc48, Yin6 and Moe1 act in the same protein complex to concertedly control ERAD and chromosome segregation. PMID: 20016281
3. Data show that Int6 acts to increase the transcriptional activity of Pap1. PMID: 16278451
4. In this study, proteasome-COP9-initiation factor proteasome subunit, Rpn7, was isolated as a high copy suppressor that rescued the proteasome defects in yin6 null cells. PMID: 17761670
亞細胞定位：

Cytoplasm.
蛋白家族：

EIF-3 subunit E family
數據庫鏈接：

KEGG: spo:SPBC646.09c

STRING: 4896.SPBC646.09c.1