Recombinant Schizosaccharomyces pombe DNA polymerase epsilon subunit D (dpb4)

中文名稱(chēng)：

龐貝裂殖酵母dpb4重組蛋白
貨號(hào)：

CSB-YP311233SXV
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

龐貝裂殖酵母dpb4重組蛋白
貨號(hào)：

CSB-EP311233SXV
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

龐貝裂殖酵母dpb4重組蛋白
貨號(hào)：

CSB-EP311233SXV-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

龐貝裂殖酵母dpb4重組蛋白
貨號(hào)：

CSB-BP311233SXV
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

龐貝裂殖酵母dpb4重組蛋白
貨號(hào)：

CSB-MP311233SXV
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

dpb4
Uniprot No.：

P87174
別名：

dpb4; SPBC3D6.09DNA polymerase epsilon subunit D; DNA polymerase II subunit D
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-210
氨基酸序列

MNQDKSKETS ELDDLALPRS IIMRLVKGVL PEKSLVQKEA LKAMINSATL FVSFLTSASG EIATNNNRKI LMPQDVLNAL DEIEYPEFSK TLKKHLEAYE LALKEKRLKL PNVSDVDNRK KAKIDAHDTT PLDEEKDELE EERIAEDIAQ NEVEQNIDDV EDLEEVNDTL DANAESPQIE TIHLTDATGN PIEDSSESDS EESLQLNDSS
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication. It is required during synthesis of the leading and lagging DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork. It has 3'-5' proofreading exonuclease activity that correct errors arising during DNA replication. It is also involved in DNA synthesis during DNA repair. The dpb3-dpb4 dimer associates with histone deacetylases, chromatin remodelers, and histones and plays a crucial role in the inheritance of histone hypoacetylation and H3K9 methylation in heterochromatin. The dpb3-dpb4 dimer is also required for the recruitment of sir2 to heterochromatin.
基因功能參考文獻(xiàn)：
1. Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex has been reported. PMID: 29109278
亞細(xì)胞定位：

Nucleus.
數(shù)據(jù)庫(kù)鏈接：

KEGG: spo:SPBC3D6.09

STRING: 4896.SPBC3D6.09.1