Recombinant Salmonella typhimurium Salmonella pathogenicity island 2 protein C (spiC)

中文名稱：

鼠傷寒沙門菌spiC重組蛋白
貨號：

CSB-YP315814SXB
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

鼠傷寒沙門菌spiC重組蛋白
貨號：

CSB-EP315814SXB
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

鼠傷寒沙門菌spiC重組蛋白
貨號：

CSB-EP315814SXB-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

鼠傷寒沙門菌spiC重組蛋白
貨號：

CSB-BP315814SXB
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

鼠傷寒沙門菌spiC重組蛋白
貨號：

CSB-MP315814SXB
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

spiC
Uniprot No.：

P0CZ04
別名：

spiC; ssaB; STM1393; Salmonella pathogenicity island 2 protein C; Secretion system apparatus protein B
種屬：

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
蛋白長度：

full length protein
表達區域：

1-133
氨基酸序列

MSEEGFMLAV LKGIPLIQDI RAEGNSRSWI MTIDGHPARG EIFSEAFSIS LFLNDLESLP KPCLAYVTLL LAAHPDVHDY AIQLTADGGW LNGYYTTSSS SELIAIEIEK HLALTCILKN VIRNHHKLYS GGV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Virulence protein that plays a central role in mammalian macrophage infection, by inhibiting phagosome-lysosome fusion and cellular trafficking. May act by disrupting the function of the mammalian HOOK3 protein, a protein involved in the cellular traffic.
基因功能參考文獻：
1. in activated macrophages, SpiC repression is more pronounced in the NirC knockout bacteria than in the WT counterpart/ reduced level of SpiC cannot effectively block IFNgamma signalling/ upregulation of iNOS expression occurs and increase in NO production PMID: 19520723
亞細胞定位：

Secreted. Cytoplasm. Note=Translocated into the cytosol of macrophages via the Salmonella pathogenicity island 2 (SPI-2) type III secretion system that functions intracellularly to translocate proteins across the phagosomal membrane. Cytoplasmic in infected macrophages.
數據庫鏈接：

KEGG: stm:STM1393

STRING: 99287.STM1393