Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4 (CIN5)

中文名稱：

Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5)
貨號：

CSB-YP336802SVG
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5)
貨號：

CSB-EP336802SVG
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5)
貨號：

CSB-EP336802SVG-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5)
貨號：

CSB-BP336802SVG
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae AP-1-like transcription factor YAP4(CIN5)
貨號：

CSB-MP336802SVG
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CIN5
Uniprot No.：

P40917
別名：

CIN5; HAL6; SDS15; YAP4; YOR028C; OR26.18; AP-1-like transcription factor YAP4; Chromosome instability protein 5; Transcription activator CIN5
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區域：

1-295
氨基酸序列

MLMQIKMDNH PFNFQPILAS HSMTRDSTKP KKMTDTAFVP SPPVGFIKEE NKADLHTISV VASNVTLPQI QLPKIATLEE PGYESRTGSL TDLSGRRNSV NIGALCEDVP NTAGPHIARP VTINNLIPPS LPRLNTYQLR PQLSDTHLNC HFNSNPYTTA SHAPFESSYT TASTFTSQPA ASYFPSNSTP ATRKNSATTN LPSEERRRVS VSLSEQVFNE GERYNNDGQL IGKTGKPLRN TKRAAQNRSA QKAFRQRREK YIKNLEEKSK LFDGLMKENS ELKKMIESLK SKLKE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcription activator involved in the regulation of genes expressed in response to environmental changes and metabolic requirements. According to genome-wide promoter binding and gene expression studies it regulates, among others, genes involved in ribosome biogenesis, and protein synthesis. It may also be involved in pleiotropic drug resistance. When overexpressed it confers increased resistance to cisplatin, the DNA-alkylating agents methylmethanosulfonate, and mitomycin C, the antimalarial drugs quinidine, mefloquine, and chloroquine, and increases cellular tolerance to sodium and lithium. Preferentially binds 5'-TTACTAA-3'.
基因功能參考文獻：
1. Mutant forms of Yap1 that are constitutively trapped in the nucleus are degraded in the absence of an oxidant signal PMID: 22707721
2. Yap4 activity is maintained in the absence of phosphorylation. However, this modification seems to be required for stability of the protein, as the non-phosphorylated form has a shorter half-life than the phosphorylated one. PMID: 19774548
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

BZIP family, YAP subfamily
數據庫鏈接：

KEGG: sce:YOR028C

STRING: 4932.YOR028C