Recombinant Rat Zinc transporter 7 (Slc30a7), partial

中文名稱：

大鼠Slc30a7重組蛋白
貨號：

CSB-YP701707RA1
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Slc30a7重組蛋白
貨號：

CSB-EP701707RA1
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Slc30a7重組蛋白
貨號：

CSB-EP701707RA1-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Slc30a7重組蛋白
貨號：

CSB-BP701707RA1
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Slc30a7重組蛋白
貨號：

CSB-MP701707RA1
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Slc30a7
Uniprot No.：

Q5BJM8
別名：

Slc30a7; Znt7; Zinc transporter 7; ZnT-7; Solute carrier family 30 member 7
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP.
基因功能參考文獻：
1. evidence that ZnT7 has a protective effect over epithelial-to-mesenchymal transition (EMT) of renal tubular epithelial cells in diabetic nephropathy and suggests that the inhibition of HG-induced EMT may be achieved through the MAPK/ERK and TGF-beta/Smad pathways. PMID: 29627824
2. Markedly increased mRNA and protein levels of ZIP7 were observed in ventricular cardiomyocytes from diabetic rats or high-glucose-treated H9c2 cells while ZnT7 expression was low. PMID: 28232492
3. The recurrent seizures plus normal diet group showed worse performances in neurological reflex tests and reduced latencies to myoclonic seizures induced by penicillin compared with the control, which was concomitant with altered expressions of ZnT-7, MT-1, MT-2, and ZIP7. PMID: 27147436
4. Data suggest that the ZnT7 (Slc30A7) may account for the inhibition of high glucose (HG)-induced epithelial-to-mesenchymal transition (EMT) in peritoneal mesothelial cells (PMCs). PMID: 23104082
亞細胞定位：

Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
蛋白家族：

Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
數據庫鏈接：

KEGG: rno:310801

STRING: 10116.ENSRNOP00000019172

UniGene: Rn.105204