Recombinant Rat Sclerostin domain-containing protein 1 (Sostdc1)

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中文名稱：

大鼠Sostdc1重組蛋白
品名簡稱：

Recombinant Rat Sostdc1 protein
貨號：

CSB-MP734096RA
說明書：

MSDS Datasheet
規格：

￥3000
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
基因名：

Sostdc1
Uniprot No.：

Q642G2
別名：

Sostdc1; Usag1; Wise; Sclerostin domain-containing protein 1; Uterine sensitization-associated gene 1 protein; USAG-1; Wnt-signaling modulator
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
來源：

Mammalian cell
分子量：

24.6kDa
表達區域：

24-206aa
氨基酸序列

FKNDATEILYSHVVKPVSAHPSSNSTLNQARNGGRHFSSTGLDRNSRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESVSPAKPAQHHRERKRASKSSKHSLS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged and C-terminal Myc-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Tris-based buffer,50% glycerol
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling.
基因功能參考文獻：
1. WISE contributes to renal dysfunction by promoting tubular atrophy and interstitial fibrosis. PMID: 23184054
2. Rat homologue of the Xenopus-secreted WNT modulator Wise is expressed in the dermal papilla and not in the non-inductive dermal sheath and was additionally expressed at high levels in the precortex and in the putative bulge region [WISE]. PMID: 15373764
3. we report the isolation, cloning, and characterization of a novel gene, uterine sensitization-associated gene-1 (UASG-1), that is preferentially expressed within the maximally sensitized/receptive rat endometrium PMID: 12390898
4. Expression of Sostdc1 exhibits a ~10-fold increase at night in the rat pineal gland. PMID: 19103603
亞細胞定位：

Secreted.
蛋白家族：

Sclerostin family
組織特異性：

Highly expressed within the maximally sensitized/receptive endometrium. Weakly expressed in brain, kidney and the female reproductive tract. Expressed in the dermal papilla (DP) and at high level in the precortex of both anagen vibrissae and pelage follic
數據庫鏈接：

KEGG: rno:266803

STRING: 10116.ENSRNOP00000008106

UniGene: Rn.2415