Recombinant Rat Rho GTPase-activating protein 24 (Arhgap24)

中文名稱：

Recombinant Rat Rho GTPase-activating protein 24(Arhgap24)
貨號：

CSB-YP725927RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Rho GTPase-activating protein 24(Arhgap24)
貨號：

CSB-EP725927RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Rho GTPase-activating protein 24(Arhgap24)
貨號：

CSB-EP725927RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Rho GTPase-activating protein 24(Arhgap24)
貨號：

CSB-BP725927RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Rho GTPase-activating protein 24(Arhgap24)
貨號：

CSB-MP725927RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Arhgap24
Uniprot No.：

Q5U2Z7
別名：

Arhgap24; DR-NR#2; Rho GTPase-activating protein 24; Down-regulated in nephrectomized rat kidney #2; Rho-type GTPase-activating protein 24
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-748
氨基酸序列

MEENCDSTEN PHSQGRQNAT KCGWLRKQGG FVKTWHTRWF VLKGDQLHYF KDEDETKPLG TIFLPGNKVI EHPCNEESPG KFLFEVVPGG ERDRMTANHE SYLLMASTQN DMEDWVKSIR RVIWGPFGGG IFGQKLEDTV RYEKRYGNRL APMLVEQCVD FIRQRGLKEE GLFRLPGQAN LVKELQDAFD CGEKPSFDSN TDVHTVASLL KLYLRELPEP VVPYAKYEDF LSCATLLSKE EEAGVKELTK QVKSLPVVNY NLLKYICRFL DEVQSYSGVN KMSAQNLATV FGPNILRPKV EDPLTIMEGT VVVQQLMSVM ISKHDRLFPK DTEPQSKPQE GPNSNNNDGH KKVTMGQLQN KENNNTKESP VRRCSWDKPE SPQRSSMDNG SPTALSGSKT NSPRNSIHKL DVSRSPPLTV KKNPAFNKGS GIVTNGSFSS SNAEGVEKTQ TTPNGSLQAR RTSSLKSSGT KMGTHSVQNG TVRMGILNTD TLGNSLNGRS MSWLPNGYVT LRDNKQKEPA GESGQHNRLS TYDNVHQQFS LMNLDDKHSV DSATWSTSSC EISLPENSNS CRSSTTTCPE QDFYGGNFED PVLDGPPQDD LSHPGDYENK SDRRSVGGRS SRATSSSDNS ETFVGNTSSN HSALHSLVSS LKQEMTKQKI EYESRIKSLE QRNLTLETEM LNLHDELDQE RKKFTMIEIK MRNAERAKED AEKRNDMLQK EMEQFFSTFG DLTVEPRRSE RGNTIWIQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
亞細胞定位：

Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction, focal adhesion. Cell projection.
數據庫鏈接：

KEGG: rno:305156

STRING: 10116.ENSRNOP00000002857

UniGene: Rn.24657