Recombinant Rat Nucleolar and coiled-body phosphoprotein 1 (Nolc1)

中文名稱：

大鼠Nolc1重組蛋白
貨號：

CSB-YP015929RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Nolc1重組蛋白
貨號：

CSB-EP015929RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Nolc1重組蛋白
貨號：

CSB-EP015929RA-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Nolc1重組蛋白
貨號：

CSB-BP015929RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Nolc1重組蛋白
貨號：

CSB-MP015929RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nolc1
Uniprot No.：

P41777
別名：

Nolc1; Nucleolar and coiled-body phosphoprotein 1; 140 kDa nucleolar phosphoprotein; Nopp140; Nucleolar 130 kDa protein; Nucleolar phosphoprotein p130
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full length protein
表達區(qū)域：

1-704
氨基酸序列

MADTGLRRVV PSDLYPLVLG FLRDNQLSEV ASKFAKATGA TQQDANASSL LDIYSFWLKS TKAPKVKLQS NGPVAKKAKK ETSSSDSSED SSEEEDKAQV PTQKAAAPAK RASLPQHAGK AAAKASESSS SEESSEEEEE KDKKKKPVQQ KAVKPQAKAV RPPPKKAESS ESESDSSSED EAPQTQKPKA AATAAKAPTK AQTKAPAKPG PPAKAQPKAA NGKAGSSSSS SSSSSSDDSE EEKKAAAPLK KTAPKKQVVA KAPVKVTAAP TQKSSSSEDS SSEEEEEQKK PMKKKAGPYS SVPPPSVSLS KKSVGAQSPK KAAAQTQPAD SSADSSEESD SSSEEEKKTP AKTVVSKTPA KPAPVKKKAE SSSDSSDSDS SEDEAPAKPV SATKSPLSKP AVTPKPPAAK AVATPKQPAG SGQKPQSRKA DSSSSEEESS SSEEEATKKS VTTPKARVTA KAAPSLPAKQ APRAGGDSSS DSESSSSEEE KKTPPKPPAK KKAAGAAVPK PTPVKKAAAE SSSSSSSSED SSEEEKKKPK SKATPKPQAG KANGVPASQN GKAGKESEEE EEDTEQNKKA AGTKPGSGKK RKHNETADEA ATPQSKKVKL QTPNTFPKRK KGEKRASSPF RRVREEEIEV DSRVADNSFD AKRGAAGDWG ERANQVLKFT KGKSFRHEKT KKKRGSYRGG SISVQVNSVK FDSE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities.
基因功能參考文獻：
1. These data show that Nopp140 reversibly associates with snoRNPs in a phosphorylation-dependent manner, but this association has no effect on pseudouridylation of rRNA. PMID: 12446766
亞細胞定位：

Cytoplasm. Nucleus, nucleolus.
數(shù)據庫鏈接：

KEGG: rno:64896

STRING: 10116.ENSRNOP00000025788

UniGene: Rn.9517