Recombinant Rat Myosin-10 (Myh10), partial

中文名稱：

大鼠Myh10重組蛋白
貨號：

CSB-YP888354RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Myh10重組蛋白
貨號：

CSB-EP888354RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Myh10重組蛋白
貨號：

CSB-EP888354RA-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Myh10重組蛋白
貨號：

CSB-BP888354RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Myh10重組蛋白
貨號：

CSB-MP888354RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Myh10
Uniprot No.：

Q9JLT0
別名：

Myh10; Myosin-10; Cellular myosin heavy chain; type B; Myosin heavy chain 10; Myosin heavy chain; non-muscle IIb; Non-muscle myosin heavy chain B; NMMHC-B; Non-muscle myosin heavy chain IIb; NMMHC II-b; NMMHC-IIB
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.
基因功能參考文獻：
1. Study suggests that NMIIB remains constitutively active in support of methamphetamine associations, continuing to drive actin polymerization, such that memories associated with methamphetamine can be selectively targeted without the need for retrieval days to weeks after learning PMID: 26239291
2. NM II maintains proper morphology of neuronal growth cones and the distal axon by regulating actin dynamics through the guanine nucleotide exchange factor-Rho GTPase signaling pathway. PMID: 24752242
3. NM II manages several major processes involved in the beta cell response to glucose, including gamma-actin protrusion and remodelling, FA assembly and turnover, and the secretory granule approach to the basal membrane PMID: 23354122
4. IIb MHC transcriptional regulation during muscle maturation to the adult state is consistent with the previously defined model of antisense-mediated coordination of genomically adjacent MHC genes, as is evident in the transcriptionally divergent euthyroid and hypothyroid states. PMID: 22262309
5. These data support the idea that Myosin II motor-force generation is a general mechanism that supports memory consolidation in the mammalian CNS. PMID: 22174310
6. myosin IIb motor activity is downstream of LTP induction and is necessary for the emergence of actin structures that stabilize an early phase of LTP, and myosin IIb activity contributes to an actin-dependent process that underlies memory consolidation PMID: 20797537
7. These results suggest that the mesangial expression of SMemb is related to glomerular matrix accumulation and that angiotensin II mediates both mesangial processes via AT1 receptors. PMID: 11961408
8. non-muscle myosin II and myosin light chain kinase are downstream targets for vasopressin signaling in the renal collecting duct PMID: 15347643
9. the SMB isoform is the predominant form expressed in rat veins, providing one possible mechanism for the faster response of veins to vasoconstrictors PMID: 17377397
10. Isolated Myh10 from rat skeletal muscle and report amino sequence. PMID: 17973598
11. These results provide important insights related to how proximal IIb MHC promoter elements regulate the increased expression of the IIb MHC gene in response to inactivity of a predominantly slow postural muscle. PMID: 19623632
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亞細胞定位：

Cell projection, lamellipodium.
蛋白家族：

TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
數據庫鏈接：

KEGG: rno:79433

STRING: 10116.ENSRNOP00000062744

UniGene: Rn.98166