Recombinant Rat Killer cell lectin-like receptor subfamily G member 1 (Klrg1), partial

中文名稱：

大鼠Klrg1重組蛋白
貨號：

CSB-YP737353RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Klrg1重組蛋白
貨號：

CSB-EP737353RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Klrg1重組蛋白
貨號：

CSB-EP737353RA-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Klrg1重組蛋白
貨號：

CSB-BP737353RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Klrg1重組蛋白
貨號：

CSB-MP737353RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Klrg1
Uniprot No.：

Q64335
別名：

Klrg1; MafaKiller cell lectin-like receptor subfamily G member 1; Mast cell function-associated antigen
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
基因功能參考文獻(xiàn)：
1. Clustering the mast cell function-associated antigen (MAFA) leads to tyrosine phosphorylation of p62Dok and SHIP and affects RBL-2H3 cell cycle. PMID: 12008030
2. The functional activities of an inhibitory receptor-the mast cell function-associated antigen [review] (mast cell function-associated antigen) PMID: 12217400
3. Interactions of the mast cell function-associated antigen with the type I Fcepsilon receptor (mast cell function-associated antigen) PMID: 12217401
4. (MAFA), selectively regulates the Fc-epsilon-RI stimulus-response coupling network and the subsequent de novo production and secretion of inflammatory mediators. PMID: 16407976
5. This provides additional indication of constitutive interactions between Fc epsilon RI and MAFA. PMID: 16797115
6. overexpression in the intestine induces intestinal epithelial cells newly to produce and release insulin PMID: 16934222
7. Regulates beta-cell-specific gene expression and function. PMID: 17149590
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亞細(xì)胞定位：

Cell membrane; Single-pass type II membrane protein.
組織特異性：

Expressed in lung mast cells.
數(shù)據(jù)庫鏈接：

KEGG: rno:58975

STRING: 10116.ENSRNOP00000020094

UniGene: Rn.10256