Recombinant Rat Inhibin beta B chain (Inhbb)

中文名稱：

大鼠Inhbb重組蛋白
貨號：

CSB-YP011720RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Inhbb重組蛋白
貨號：

CSB-EP011720RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Inhbb重組蛋白
貨號：

CSB-EP011720RA-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Inhbb重組蛋白
貨號：

CSB-BP011720RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Inhbb重組蛋白
貨號：

CSB-MP011720RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Inhbb
Uniprot No.：

P17491
別名：

Inhbb; Inhibin beta B chain; Activin beta-B chain
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區(qū)域：

297-411
氨基酸序列

GLEC DGRTSLCCRQ QFFIDFRLIG WNDWIIAPTG YYGNYCEGSC PAYLAGVPGS ASSFHTAVVN QYRMRGLNPG PVNSCCIPTK LSSMSMLYFD DEYNIVKRDV PNMIVEECGC A
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
基因功能參考文獻：
1. Activin B induced phosphorylation and activation of Smad1/5/8, the BMP-regulated (BR)-Smads. The stimulation of hepcidin transcription by activin B was mediated by ALK2 and ActRIIA, receptors for the TGF-beta family. PMID: 27922109
2. RhoA regulates Activin B-induced stress fiber formation and migration of Bone marrow-derived mesenchymal stem cells. PMID: 27693126
3. Results identified Inhbb as one factor mediating the proliferative effect of Pdx-1 on islet cells. PMID: 27620967
4. Fluorine had no effect on the expression of androgen binding protein and inhibin B mRNA in testis sertoli cells of Sprague Dawley rats. PMID: 21033444
5. p,p'-DDE could inhibit the expression of inhibin B in rat Sertoli cells. PMID: 19877505
6. TNFalpha and IL1alpha supresses inhibin B secretion and expression in rat Sertoli cells PMID: 21256182
7. inhibin is a major regulator of FS, both by transcriptional and nontranscriptional mechanisms. PMID: 14561646
8. inhibin B is the major inhibin in the male rat and that levels relate to Sertoli cell number and activity. PMID: 15070852
9. inhibins A and B differentially antagonize the actions of activins and BMPs to control adrenocortical C(19) steroid production PMID: 16601134
10. Regulation of pituitary Nr5a2, Inhba, and Inhbb transcripts was limited to young animals. PMID: 17344471
11. propose hypothesis that increase in growth rate subsequent to weaning signals circulating inhibin B levels to fall and pituitary adenylate cyclase-activating polypeptide to decrease and these events facilitate the rise in follicle-stimulating hormone b PMID: 18160680
12. The effect of steroidogenic substrates and follicle stimulating hormone on steroid, inhibin A and B, Pro-alphaC and activin A production was evaluated. PMID: 19464342
13. Bacterial lipopolysaccharide increased the production of interleukin 1alpha and activin A, and reduced production of inhibin B, in Sertoli cells from immature male rats. PMID: 19524137
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亞細胞定位：

Secreted.
蛋白家族：

TGF-beta family
組織特異性：

Alpha- and beta-B subunits are the predominant forms found in rat testis. Also expressed in ovary.
數(shù)據(jù)庫鏈接：

KEGG: rno:25196

STRING: 10116.ENSRNOP00000065153

UniGene: Rn.35074