Recombinant Rat Hepatocyte nuclear factor 3-gamma (Foxa3)

中文名稱：

大鼠Foxa3重組蛋白
貨號：

CSB-YP008796RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Foxa3重組蛋白
貨號：

CSB-EP008796RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Foxa3重組蛋白
貨號：

CSB-EP008796RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Foxa3重組蛋白
貨號：

CSB-BP008796RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Foxa3重組蛋白
貨號：

CSB-MP008796RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Foxa3
Uniprot No.：

P32183
別名：

Foxa3; Hnf3g; Tcf-3g; Tcf3gHepatocyte nuclear factor 3-gamma; HNF-3-gamma; HNF-3G; Forkhead box protein A3
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full length protein
表達區域：

1-354
氨基酸序列

MLGSVKMEAH DLAEWSYYPE AGEVYSPVNP VPTMAPLNSY MSLNPLSSPY PPGGLQASPL PTGPLAPPAP TAPLGPTFPG LGAGSGTGGS ASGYGAPGPG LVHGKEMAKG YRRPLTHAKP PYSYISLITM AIQQAPGKML TLSEIYQWIM DLFPYYRENQ QRWQNSIRHS LSFNDCFVKV ARSPDKPGKG SYWALHPSSG NMFENGCYLR RQKRFKLEEK AKKGNSATSA TRNGTVGSAT SATTTAATAV TSPAQPQPTP PSEPEAQSGE DVGGLDCASP PSSAPYFTGL ELPGELKLDA PYNFNHPFSI NNLMSEQTST PSKLDVGFGG YGAESGEPGV YYQSLYSRSL LNAS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis.
基因功能參考文獻：
1. data suggested a protection role for Foxa3 during the progression of liver fibrosis in biliary atresia, and thereby supported increasing Foxa3 as a targeted treatment strategy. PMID: 28358366
2. FOXA3 and HNF4alpha are powerful transcription factors for inducing rat bone marrow mesenchymal stem cells to differentiate into functional hepatocyte-like cells. PMID: 25896100
亞細胞定位：

Nucleus.
組織特異性：

Liver.
數據庫鏈接：

KEGG: rno:25100

STRING: 10116.ENSRNOP00000019219

UniGene: Rn.10949